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October 1992

Gist Recall in Multiple Sclerosis

Author Affiliations

From the Department of Neurology (Neurobehavioral Program), Emory University School of Medicine and Wesley Woods Center, Atlanta, Ga (Dr Goldstein); the Departments of Neurology and Microbiology, The University of Texas Medical Branch, Galveston (Dr McKendall);and the Departments of Behavioral Medicine, Psychiatry, and Neurology, West Virginia University School of Medicine, Morgantown (Dr Haut).

Arch Neurol. 1992;49(10):1060-1064. doi:10.1001/archneur.1992.00530340080021

• This study examined gist recall (memory for important story ideas) in patients with multiple sclerosis. Twelve patients with clinically probable or definite multiple sclerosis and 10 neurologically intact control subjects were read prose passages from the Wechsler Memory Scale-Revised Logical Memory subtest. The idea units from these passages contained low, medium, and high information content to the stories. In comparison with the control subjects, the patients recalled fewer total elements over immediate and delayed conditions. However, similar to controls, they recalled more ideas that were of high rather than low or medium importance. These results suggest that semantic sensitivity to important ideas of narratives is a relatively preserved feature in multiple sclerosis.

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