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November 1992

The Biochemical Basis of Neuropharmacology

Author Affiliations

Washington, DC

Arch Neurol. 1992;49(11):1109-1110. doi:10.1001/archneur.1992.00530350019005

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


This is the sixth edition of the classic book that provides an introductory overview to neuropharmacology. As with earlier editions, this work is notable for its clarity, easy reading style, and the high quality of the extensive figures and tables. The early chapters provide an excellent introduction to general neuroscience as well as to basic neuropharmacology. Particularly good in this regard are the sections dealing with molecular foundations of neuropharmacology, receptors, and second messenger systems.

The strength of The Biochemical Basis of Neuropharmacology continues to be its comprehensive summary of classic neurotransmitters and their receptors, with descriptions of even some of the most recently described receptors such as the D3, D4, and D5 dopamine receptors. The chapters on acetylcholine, norepinephrine and epinephrine, dopamine, serotonin, and histamine are all outstanding.

The chapter dealing with amino acid transmitters is not quite as comprehensive but still provides a good synopsis

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