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January 1993

Predictive Value of Magnetic Resonance Imaging in Temporal Lobe Epilepsy Surgery

Author Affiliations

From the University of Alabama at Birmingham Epilepsy Center, Departments of Neurology (Drs Kuzniecky and Faught), Neurosurgery (Dr Morawetz), and Biostatistics and Biomathematics (Ms Burgard and Dr Bartolucci), University of Alabama at Birmingham.

Arch Neurol. 1993;50(1):65-69. doi:10.1001/archneur.1993.00540010059018

• The predictive value of magnetic resonance imaging (MRI) was assessed by a prospective study of 34 patients selected for surgical treatment of temporal lobe epilepsy. The MRIs were interpreted using standardized visual diagnostic criteria and the imaging findings were correlated with the surgical outcome. Lateralized MRI abnormalities were found in 25 (74%) of 34 patients. Significant associations were found between either the presence of a restricted foreign-tissue lesion or hippocampal atrophy and an excellent surgical outcome. An abnormal MRI had an 82% predictive value and a normal MRI had a 56% predictive value for surgical success. A history of febrile convulsions and the presence of hippocampal atrophy best predicted outcome (predictive value, 86%). These results suggest that specific MRI findings in candidates for temporal lobe epilepsy surgery are predictive of surgical outcome. The information provided by MRI may be of value for counseling patients prior to surgical intervention.

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