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April 1993

Albendazole Therapy for Giant Subarachnoid Cysticerci-Reply

Author Affiliations

Department of Neurology Luis Vernaza Hospital PO Box (09-01) 3734 Guayaquil, Ecuador South America

Arch Neurol. 1993;50(4):348. doi:10.1001/archneur.1993.00540040009007

In Reply.  —We described four patients with giant subarachnoid cysticerci who were successfully treated with albendazole.1 As noted in our article, the patients did not have intracranial hypertension or hydrocephalus before the trial, and dexamethasone treatment was started before albendazole administration and its use was prolonged some days after that trial had been completed. Therefore, our patients differ from that described by Noboa in both the clinical picture and the timing of dexamethasone administration. Probably, such differences accounted for the "deleterious effect of albendazole" reported in Noboa's letter.When our article was submitted for publication in the Archives, I was working at the Ecuadorian Institute of Social Security. Now, as a member of the Department of Neurology of Luis Vernaza Hospital (Guayaquil, Ecuador), I have had the opportunity to review the record of the patient described by Noboa. The patient was totally blind before albendazole administration, and funduscopic examination

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