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May 1993

Spinal Fluid Cells and Protein in Amyotrophic Lateral Sclerosis

Author Affiliations

From the Amyotrophic Lateral Sclerosis Research Foundation (Drs Norris, Ü, and Mukai); and the Departments of Neurology (Drs Norris and Ü), and Pathology (Dr Burns), California Pacific Medical Center, San Francisco; and Apollo/Hewlitt Packard Computers, Chelmsford, Mass (Mr Norris). Dr Mukai is currently with the Department of Neurology, Nagoya (Japan) National Hospital; Mr Norris is with Dow-Jones, Princeton, NJ.

Arch Neurol. 1993;50(5):489-491. doi:10.1001/archneur.1993.00540050041012

• The cerebrospinal fluid total protein in 385 cases of sporadic amyotrophic lateral sclerosis showed no relationship to survival, but it was related to survival time in 34 cases of familial amyotrophic lateral sclerosis. Infrequent and mild pleocytosis, and oligoclonal bands seemed to have no clinical significance in well established cases of amyotrophic lateral sclerosis.