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February 1994

Neuropathogenic Viruses and Immunity

Author Affiliations

Iowa City, Iowa

Arch Neurol. 1994;51(2):114-115. doi:10.1001/archneur.1994.00540140016005

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Neuropathogenic Viruses and Immunity, edited by Specter, Bendinelli, and Friedman and a volume in the series entitled Infectious Agents and Pathogenesis, represents a comprehensive review of neurovirology written by more than 30 distinguished neuroscientists. Divided into four sections, "General Information," "Animal Models," "Human Infections of the Central Nervous System," and "Perspectives," the book begins with a succinct, well-documented introductory chapter, written by the editors, that defines the spectrum of virus-induced human disease. The subsequent, brief section ("General Information") includes a delightful chapter,"Immune Responses and the Central Nervous System," coauthored by Drs William Tyor and Richard-Johnson, that should appeal to all readers.

The "Animal Models" section contains well-written material regarding Theiler's virus, scrapie, visna, and other animal retroviruses. Many readers may ignore these chapters and move quickly to the sections on human disease that follow. However, these animal models, an essential component of neurovirology, deserve attention since they provide important insights

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