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March 1994

Subacute Inflammatory Demyelinating Polyneuropathy: Not a New Concept-Reply

Author Affiliations

Department of Neurology United Medical and Dental Schools Guy's Hospital London, United Kingdom SEI 9RT

Arch Neurol. 1994;51(3):235-236. doi:10.1001/archneur.1994.00540150020009

in reply  I am pleased to acknowledge that Oh discussed the concept of an intermediate form of neuropathy between Guillain-Barré syndrome and chronic idiopathic demyelinating polyradiculoneuropathy in 1978 in the light of concepts then current in an article that we would have been pleased to quote if we had been aware of its existence. However, I find Oh's response confusing, since he appears to equate subacute demyelinating neuropathy with CIDP in the first sentence of his penultimate paragraph, and the modern definition of CIDP would classify nine of his 10 patients as having CIDP and not SIDP (subacute idiopathic demyelinating polyradiculopathy). Since we now have definitions of Guillain-Barré syndrome reaching its nadir within 4 weeks and CIDP reaching its nadir after 2 months (8 weeks would be better) from international committees, I adhere to the view that only the intermediate group should be considered to have SIDP. If patients with