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March 1994

Ataxic Neuropathy Associated With Human Immunodeficiency Virus Seroconversion

Author Affiliations

Department of Neurology Hospital Puerta de Hierro c/San Martin de Porres 4 28035 Madrid Spain

Arch Neurol. 1994;51(3):236. doi:10.1001/archneur.1994.00540150022010

Different authors have described a variety of peripheral neuropathies during human immunodeficiency virus (HIV) infection.1,2 Among them, we have found only one case of subacute ataxic neuropathy, described by Elder et al.3 We now describe a case compatible with ganglioneuronitis both clinically and neurophysiologically, coincidental with HIV seroconversion.

Report of a Case.  In February 1992, a 28-year-old male intravenous drug abuser, with no other antecedents of interest, had an acute hepatitis 10 days before admission. Five days later, he developed a neurologic deficit with paresthesias and loss of tactile and pain sensation in his hands and feet, incoordination and slight weakness in all extremities, as well as inability to stand. On admission, he was afebrile and icteric and his liver edge was tender and palpable 5 cm below the right costal margin. Neurological examination revealed a severe distal loss of positional and vibratory senses, mild hypoalgesia and homogeneous

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