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May 1996

Metabolic Myopathies

Author Affiliations

London, England

Arch Neurol. 1996;53(5):408. doi:10.1001/archneur.1996.00550050030018

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This 13-chapter book comes from a respected multidisciplinary group of myologists who are affiliated with Oxford University. The first five chapters describe the clinical approach to the patients who are suspected of having a metabolic myopathy, and summarize the role and the range of findings that may be seen with electromyography, muscle biopsy and magnetic resonance spectroscopy, and the normal response of skeletal muscle during exercise. These are excellent introductions to the topics written without assumption of any prior knowledge of these areas. The prominence of the chapter on the use of magnetic resonance spectroscopy in metabolic muscle disease reflects the particular expertise of this group, and this complex subject is lucidly explained. While conceding that there have been few studies to determine the sensitivity and specificity of magnetic resonance spectroscopy, the authors are enthusiastic proponents of its usefulness. However, the general availability of magnetic resonance spectroscopy and personnel with

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