We appreciate the interest expressed by Dodrill and Batzel in our report on the relationship of quality of life to neuropsychological factors in patients with epilepsy.1 They express the following concerns regarding our study: (1) lack of acknowledgment of research comparing the WPSI with neuropsychological tests, (2) grouping of mood with mental ability factors, and (3) underemphasis of the relationship between QOLIE-89 scales and mood and lack of validation for the QOLIE-89 cognitive scales.First, the authors cite 3 references in which they claim that "the WPSI has been directly related to neuropsychological performance." All 3 of these references are to book chapters that did not actually examine the relationship of specific neuropsychological abilities to quality-of-life domains. Instead, WPSI scales were compared between 4 categories of IQ ranges or 4 categories of global neuropsychological impairment. In addition, they state that "comparisons between the WPSI and neuropsychological tests
Perrine K, Devinsky O, Hermann BP, Meador KJ, Vickrey BG, Cramer JA. Epilepsy-Reply. Arch Neurol. 1996;53(6):476–477. doi:10.1001/archneur.1996.00550060018004
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