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October 1996

AIDS and Neurology

Author Affiliations

Rochester, NY

Arch Neurol. 1996;53(10):963-964. doi:10.1001/archneur.1996.00550100029010

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AIDS and Neurology is written by 2 of the leading investigators in this field. The book consists of 15 chapters and appendixes. The first chapter introduces the reader to basic knowledge on the virus structure, life cycle, and interactions with host immune system. In this chapter, the overview of neurological complications sets the stage for the following chapters.

The book can be divided into 2 main sections. The first section consists of neurological manifestations either directly or indirectly related to the human immunodeficiency virus (HIV) infection in the relatively immunocompetent and more severe immune-suppressed individual. Topics include HIV-associated dementia complex and spinal cord disease, with emphasis on vacuolar myelopathy, peripheral neuropathy, and muscle disease. The entire section is very well written, but definitely the highlight of this section is the chapter on HIV dementia. In 28 pages the authors exhaustively review the epidemiology, clinical presentation, investigations, pathology, current hypotheses on

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