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November 1996

Management of Migraine

Author Affiliations

Kansas City, Kan

Arch Neurol. 1996;53(11):1100. doi:10.1001/archneur.1996.00550110036010

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This brief volume of 150 pages deals primarily with the drugs used in migraine treatment, although there are chapters on classification, symptoms and pathogenesis, and differential diagnosis. The separate chapters on abortive pharmacological treatment and preventive pharmacological treatment are the most useful since they detail dosages and side effects of the many pharmaceuticals in use, give the author's comparative evaluation of the drugs and his preferences for treatment. The detailed description of the individual research studies on pharmacological treatment is an unusual and particularly helpful feature of the book.

The chapter on pathogenesis is less successful; the concept of neurogenic inflammation, for example, is not well explained. The reader is left with the idea that current thinking is that migraine pain derives from neurogenic inflammation of the extracranial arteries—a concept that is highly controversial.

The discussion of the relationship between tension-type headache and migraine is brief; there is no mention

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