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May 1997

Lou Gehrig and Amyotrophic Lateral Sclerosis: Is Vitamin E to Be Revisited?

Author Affiliations

From the Department of Neurology, The Ohio State University, Columbus.

Arch Neurol. 1997;54(5):527-528. doi:10.1001/archneur.1997.00550170013008

Investigators are beginning to reexamine the use of vitamin E for the treatment of amyotrophic lateral sclerosis. Vitamin E was isolated in the 1920s, and the results of animal studies led rapidly to clinical use. Regrettably, vitamin E did not ameliorate the progression of amyotrophic lateral sclerosis for Lou Gehrig, but more recent advances may identify subpopulations that do respond to vitamin E.

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