We read with interest the article by Ghika and Bogousslavsky1 who found that 80% of their patients diagnosed as having progressive supranuclear palsy (PSP) had presymptomatic hypertension, suggesting that this might be a major feature in the diagnosis of PSP. However, we have not been able to confirm this finding in the setting of a multicenter case-control study of patients affected by PSP, designed to discern environmental and genetic factors possibly accounting for the pathogenesis of this disorder.2