VLADIMIRHACHINSKIMD, FRCPC, DScMed
ADDRESSING causative rather than symptomatic treatments, I suggest that the following are the appropriate goals of antidementia therapy: (1) to improve the patient's capacity to perform the basic or instrumental activities of daily living; (2) to improve the quality of life of the patient and/or the caregiver; (3) to improve memory and other cognitive and behavioral functions to the extent that this leads to clinically relevant improvements; and (4) to slow the course of the disease with respect to measurable cognitive decline and the level of care required, in comparison with placebo therapy.
Pryse-Phillips W. Do We Have Drugs for Dementia?No. Arch Neurol. 1999;56(6):735–737. doi:10.1001/archneur.56.6.735