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Letters to the Editor
June 1999

Anticardiolipin Antibodies—Reply

Arch Neurol. 1999;56(6):760. doi:

In reply

We thank Howell for his comments regarding our article. Indeed, the series published by Sussman et al1 adds important information to our knowledge concerning possible associations between anticardiolipin antibodies and intracranial hypertension. We appologize for our failure to cite their work that was published after our manuscript was completed but prior to its submission to the ARCHIVES. According to Howell, Sussman et al included patients with dural sinus thrombosis in their series whereas such patients were not included in our series. Moreover, dural sinus thrombosis may present in a benign fashion mimicking benign intracranial hypertension (pseudotumor cerebri).2 Neuroimaging studies, which are mandatory for the diagnosis of dural sinus thrombosis, are not reported for their patients and therefore, the true incidence of benign intracranial hypertension in the series of Sussman et al is unknown. Nevertheless, these 2 studies provide support to the association of anticardiolipin antibodies with intracranial hypertension.

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