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Book Reviews
January 2000

Introduction to the Blood-Brain Barrier: Methodology, Biology and Pathology

Arch Neurol. 2000;57(1):137-138. doi:

This book consists of 1 introductory chapter and 5 parts, each composed of several chapters. There are a total of 50 chapters. Each part deals with an important topic regarding the study of the blood-brain barrier. Parts I through V are entitled "Methodology," "Transport Biology," "General Aspects of CNS Transport," "Signal Transduction/Biochemical Aspects," and "Pathophysiology in Disease States." Individual chapters describe various subtopics, ranging from methods and techniques used to study the function of the blood-brain barrier and physiology and biochemistry of its transport processes to the pathophysiological basis of its dysfunction. As a whole, this book is a well-written account of the current state of understanding of basic and applied aspects of the blood-brain barrier. Each of its various chapters is written by 1 to 3 authors (a total of 90 contributing authors) who have made significant contributions and are currently active in their respective areas of blood-brain barrier research. The material covered in this book would be of immense benefit to students, residents, scientists, and clinicians interested in an introduction as well as a review of the current state of knowledge of the blood-brain barrier.