CHRONIC headache is present in most patients with postconcussional syndrome, and at least a transient headache is nearly a universal symptom following mild to moderate head injury. In my view, there currently exists a substantial body of data that support the neurobiological basis of chronic posttraumatic headache. Here are some of the key elements that support this position.
• The selective vulnerability to head-traumatic injury and sequelae may be explained in part by genetic, gender-related, or neuroanatomical factors, or principles of physics.
Saper JR. Posttraumatic Headache: A Neurobehavioral Disorder. Arch Neurol. 2000;57(12):1776–1778. doi:10.1001/archneur.57.12.1776
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