In the article by Wolozin and colleagues,1 use of "statin" cholesterol-lowering drugs is observationally associated with lower rates of Alzheimer disease (AD). Haley and Dietschy,2 in the accompanying editorial, make the vitally important point that causality cannot be affirmed with certainty due to indication bias.
Beatrice Alexandra Golomb, Beth Jaworski. Statins and Dementia. Arch Neurol. 2001;58(7):1169–1170. doi: