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November 2001

Impact of the Human Genome Sequence on Neurology and Neuroscience

Arch Neurol. 2001;58(11):1750-1751. doi:10.1001/archneur.58.11.1750

THE RECENTLY completed working draft sequence of the human genome is a tool for identifying genetic causes of neurological diseases and therapeutic targets for their treatment. The emerging map contains 30 000 to 35 000 protein-coding genes and more than 2 million markers to help locate disease-causing genes.1,2 These landmarks form a useful guide to navigate through vast quantities of sequence, to identify disease genes that are mutated, and to screen for therapeutic targets that might offer hope for treatments.

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