OCULOSYMPATHETIC paralysis, also known as Horner syndrome, develops when a lesion in the brain, spinal cord, or peripheral nerve fibers interrupts the sympathetic innervation to the eye. The result is a droopy upper eyelid, an elevation of the lower lid, a slightly sunken eye, a smaller pupil, loss of sweating on the affected side, and an acutely red eye. This condition has also been observed in Russian cosmonauts during space flight, where it results from dysfunction of the sympathetic innervation.1
Appenzeller O, Amm M, Walker S. An Ancient Eye. Arch Neurol. 2002;59(3):480–481. doi:10.1001/archneur.59.3.480
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