We found the article by Stern et al1 about dementia in patients with human immunodeficiency virus (HIV) to be very interesting, especially the associations between dementia and depression, hematocrit, and hemoglobin. We were able to conduct a similar analysis with the Veterans with HIV/AIDS [acquired immunodeficiency syndrome] Cohort Study (VACS)2 data. Although our outcome variable was slightly different and was measured at baseline by a single question on the primary care provider survey ("Does this patient have cognitive impairments or dementia?"), we also found depression, hematocrit level, hemoglobin level, and CD4 count to be associated with provider-reported dementia and cognitive impairments.
McGinnis KA, Justice AC. Factors Associated With Dementia and Cognitive Impairments in Veterans With Human Immunodeficiency Virus. Arch Neurol. 2002;59(3):490. doi:
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