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July 2003

The Diagnosis of Alzheimer Disease Before It Is Alzheimer Dementia

Author Affiliations

Copyright 2003 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2003

Arch Neurol. 2003;60(7):1023. doi:10.1001/archneur.60.7.1023-a

The study by Riemenschneider et al1 suggests that markers of Alzheimer disease (AD) can be detected when patients are in the mild cognitive impairment (MCI) stage and that these markers are associated with the progression of cognitive symptoms. We wish to place the results of their study in a clinical context to imply that the detection of the biological "fingerprint" of AD in patients with MCI might be sufficiently accurate for clinical decisions.