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April 2004

Cortical Stimulation for Parkinsonism

Arch Neurol. 2004;61(4):606. doi:10.1001/archneur.61.4.606-a

In a recent issue of the ARCHIVES, Kleiner-Fisman et al1 reported the use of motor cortical stimulation for multiple system atrophy (MSA)–related parkinsonism. A few comments are in order. We introduced extradural motor cortical stimulation for Parkinson disease (PD) in 1998 and have since reported 3 cases.2-4 We observed that low-frequency but not high-frequency extradural motor cortical stimulation relieved all signs of PD in a range comparable with deep brain stimulation (DBS). Our results have been confirmed by other European groups (unpublished observations). We also described a now deceased patient with MSA and parkinsonian symptoms.2

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