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History of Neurology: Seminal Citation
July 2004

Postpolio Syndrome

Author Affiliations

From the Departments of Rehabilitation (Dr Nollet) and Neurology (Dr de Visser), Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.



Arch Neurol. 2004;61(7):1142-1144. doi:10.1001/archneur.61.7.1142

Postpolio syndrome (PPS) refers to a decline of muscle function usually occurring 30 to 40 years after the acute polio episode.1 This syndrome has been widely recognized only during the last decades, when many people affected by the large epidemics of the previous century experienced new muscle weakness as they grew older.2 However, cases of late-onset weakening following poliomyelitis were already reported at the end of the 19th century.

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