We appreciate the comments by Dr Wang on our article. In Taiwan, the incidence of JE has been significantly reduced following vaccination programs. In 1997, the incidence of patients in Taiwan with confirmed JE was 0.03 per 100 000 people.1,2 Recently 3 more cases of JE have been reported in southern Taiwan.2 The seroconversion rate was 85% after more than 2 doses of vaccine, emphasizing that at least 15% of the population in this region are at risk for developing JE.1
Misra UK, Kalita J. Comparison of Magnetic Resonance Imaging Abnormalities in Japanese Encephalitis and Acute Necrotizing Encephalopathy of Childhood—Reply. Arch Neurol. 2004;61(7):1150. doi:https://doi.org/10.1001/archneur.61.7.1150
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