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February 2007

Sex as a Prognostic Factor for Surgical Outcome in Mesial Temporal Lobe Epilepsy

Arch Neurol. 2007;64(2):288. doi:10.1001/archneur.64.2.288-a

Burneo and colleages1 recently reported that ethnicity and socioeconomic status are not isolate predictors for seizure control in surgical mesial temporal lobe epilepsy associated with hippocampal sclerosis (MTLE-HS). These interesting results perhaps suggest that studies analyzing surgical outcome in MTLE-HS conducted in populations with diverse socioeconomic status or ethnic backgrounds might have broader external validity. However, they also found that men had better outcomes than women. If this finding is accurate, it could have important neurobiological or clinical consequences. However, we feel this last result needs some further consideration.

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