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August 2007

Babinski, Pseudo-Babinski, and Dystonia—Reply

Author Affiliations

Copyright 2007 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2007

Arch Neurol. 2007;64(8):1209. doi:10.1001/archneur.64.8.1209-a

In reply

We thank Dr Horstink and colleagues for their interest in our article1 and for their informative comments regarding the neurophysiological basis of the extensor plantar response in patients with pyramidal tract dysfunction and the putative neurophysiological mechanisms responsible for the “pseudo-Babinski” response in patients with dystonia. The focus of our manuscript was to broaden the phenotype of DRD and to highlight the fact that patients with genetically confirmed DRD may have “cerebellar signs” that may also improve in response to levodopa therapy. Nevertheless, some points raised by Horstink et al deserve discussion.