Multiple scattered microbleeds on gradient-echo magnetic resonance imaging may be found as a consequence of cerebral microangiopathy due to hypertension, amyloid angiopathy, or hemorrhagic conversion of cardiac emboli or artery to artery embolization.1 Amyloid deposition in the setting of Alzheimer disease or intracerebral hemorrhage can be studied in humans by performing carbon 11 ([11C])–labeled Pittsburgh Compound B positron emission tomography. This positron emission tomography tracer has a high affinity for vascular as well as plaque β-amyloid and is increasingly being used in the evaluation of cognitive disturbance and stroke.2
Vanacker P, Nelissen N, Van Laere K, Thijs VN. Scattered Cerebral Microbleeds Due to Cardiac Myxoma. Arch Neurol. 2009;66(6):796–797. doi:10.1001/archneurol.2009.63
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