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May 2011

Statins After Intracerebral Hemorrhage: To Treat or Not to Treat

Author Affiliations

Author Affiliations: Department of Medicine (Neurology), Duke Stroke Center, Duke University, and Durham VA Medical Center, Durham, North Carolina.

Arch Neurol. 2011;68(5):565-566. doi:10.1001/archneurol.2010.349

Decision analysis provides a tool for explicitly considering the potential impact of a therapeutic intervention by simultaneously evaluating a variety of factors that might affect its effectiveness, taking into account patient views of different health outcomes on quality of life. By varying the various estimates across an array of plausible values, it is possible to gain an understanding of the range of likely benefits and harms associated with differing treatment strategies. Westover et al used decision analysis to determine under what clinical circumstances statin therapy should be avoided in patients with a history of intracerebral hemorrhage, concluding that

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