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September 2023, Vol 80, No. 9, Pages 882-1004

Viewpoint

E-Cigarettes and Stroke Risk—Present Uncertainties and Future Directions

Abstract Full Text
JAMA Neurol. 2023;80(9):883-884. doi:10.1001/jamaneurol.2023.2050

This Viewpoint describes the need for epidemiological studies of the association between e-cigarette use and risk of stroke to inform decision-making among patients, health care practitioners, and policy makers.

Considering Patient Sex in Prescribing CGRP Receptor Antagonists for Short-Term Treatment of Migraine

Abstract Full Text
JAMA Neurol. 2023;80(9):885-886. doi:10.1001/jamaneurol.2023.2335

This Viewpoint describes the relevance of sex-specific differences in the treatment of migraine, including in evidence from trials of CGRP therapeutics, and the clinical implications for decision-making in practice and trial design.

On the Brain

Sleeping in Airports

Abstract Full Text
JAMA Neurol. 2023;80(9):887-888. doi:10.1001/jamaneurol.2023.1867

This essay describes the author’s experience of sleeping in an airport because of an April blizzard.

Editorial

Reframing Lesional Epilepsy as a Network Disease

Abstract Full Text
JAMA Neurol. 2023;80(9):889-890. doi:10.1001/jamaneurol.2023.1080
Original Investigation

Mapping Lesion-Related Epilepsy to a Human Brain Network

Abstract Full Text
open access
JAMA Neurol. 2023;80(9):891-902. doi:10.1001/jamaneurol.2023.1988

This case-control study evaluates the locations of epilepsy-associated lesions with respect to specific brain regions and networks.

Dementia Risk and Disadvantaged Neighborhoods

Abstract Full Text
has audio
JAMA Neurol. 2023;80(9):903-909. doi:10.1001/jamaneurol.2023.2120

This cohort study determines whether there is a difference in dementia incidence among Veterans Health Administration enrollees by neighborhood disadvantage as assessed by the Area Deprivation Index.

Association Between Thrombectomy and Functional Outcomes in Pediatric Patients With Acute Ischemic Stroke From Large Vessel Occlusion

Abstract Full Text
JAMA Neurol. 2023;80(9):910-918. doi:10.1001/jamaneurol.2023.2303

This case-control study evaluates whether pediatric patients with acute large vessel occlusion (LVO) stroke who undergo thrombectomy have better clinical outcomes than matched patients managed conservatively.

Excess Mortality With Alzheimer Disease and Related Dementias as an Underlying or Contributing Cause During the COVID-19 Pandemic in the US

Abstract Full Text
open access
JAMA Neurol. 2023;80(9):919-928. doi:10.1001/jamaneurol.2023.2226

This cross-sectional study compares COVID-19 pandemic-era excess deaths associated with Alzheimer disease or related dementias between year 1 and year 2 overall and by age, sex, race and ethnicity, and place of death.

Associations of Sex, Race, and Apolipoprotein E Alleles With Multiple Domains of Cognition Among Older Adults

Abstract Full Text
open access
JAMA Neurol. 2023;80(9):929-939. doi:10.1001/jamaneurol.2023.2169

This genetic association study analyzes data from 4 Alzheimer disease and cognitive aging cohorts to investigate whether sex and race modify associations of APOE ε4 and ε2 with cognition.

Development and Validation of a Postprocedural Model to Predict Outcome After Endovascular Treatment for Ischemic Stroke

Abstract Full Text
JAMA Neurol. 2023;80(9):940-948. doi:10.1001/jamaneurol.2023.2392

This prognostic study investigates the effectiveness of a prognostic tool to predict the functional outcome of individual patients after endovascular treatment for ischemic stroke.

Association of Early-, Middle-, and Late-Life Depression With Incident Dementia in a Danish Cohort

Abstract Full Text
JAMA Neurol. 2023;80(9):949-958. doi:10.1001/jamaneurol.2023.2309

This cohort study investigates the association of dementia with early-, middle-, and late-life depression in a Danish cohort.

Outcomes and Treatment Approaches for Super-Refractory Status Epilepticus: A Systematic Review and Meta-Analysis

Abstract Full Text
JAMA Neurol. 2023;80(9):959-968. doi:10.1001/jamaneurol.2023.2407

This study attempts to assess clinical characteristics, causes, outcomes, prognostic factors, and treatment approaches for patients with super-refractory status epilepticus.

Prevalence and Clinical Implications of a β-Amyloid–Negative, Tau-Positive Cerebrospinal Fluid Biomarker Profile in Alzheimer Disease

Abstract Full Text
open access
JAMA Neurol. 2023;80(9):969-979. doi:10.1001/jamaneurol.2023.2338

This cohort study assesses the memory clinic prevalence and prognosis of individuals with a β-amyloid–negative, tau-positive cerebrospinal fluid biomarker profile.

Exome Sequencing and the Identification of New Genes and Shared Mechanisms in Polymicrogyria

Abstract Full Text
open access
JAMA Neurol. 2023;80(9):980-988. doi:10.1001/jamaneurol.2023.2363

This genetic association study assesses germline genetic causes of polymicrogyria in a large cohort and considers novel polymicrogyria gene associations.

Brief Report

Immunoglobulin A Antibodies Against Myelin Oligodendrocyte Glycoprotein in a Subgroup of Patients With Central Nervous System Demyelination

Abstract Full Text
open access
JAMA Neurol. 2023;80(9):989-995. doi:10.1001/jamaneurol.2023.2523

This cross-sectional study examines laboratory and imaging data for patients with demyelinating central nervous system disease to investigate the frequency of MOG-IgA and associated clinical features.

Images in Neurology

Visual Evoked Potentials in Acute Retinal Migraine

Abstract Full Text
has active quiz
JAMA Neurol. 2023;80(9):996-997. doi:10.1001/jamaneurol.2023.1889

This case report describes monocular blurred vision and photopsia with headache.

Popeye Sign in Hereditary Transthyretin Amyloidosis

Abstract Full Text
has active quiz
JAMA Neurol. 2023;80(9):998-999. doi:10.1001/jamaneurol.2023.1975

This case report describes a 63-year-old man who developed dysesthesia in his feet and was misdiagnosed with chronic inflammatory demyelinating polyradiculoneuropathy.

Research Letter

Evaluation of Crowdsourced Fundraising to Cover Health Care Costs for Neurological Conditions in the US

Abstract Full Text
JAMA Neurol. 2023;80(9):1000-1002. doi:10.1001/jamaneurol.2023.2235

This cross-sectional study characterizes the use of and rationale for crowdsourced fundraising by patients with neurological illnesses and their family members.

Characteristics of Emergency Department Visits Among Older Adults With Dementia

Abstract Full Text
JAMA Neurol. 2023;80(9):1002-1004. doi:10.1001/jamaneurol.2023.2244

This cross-sectional study examines emergency department use among older adults with Alzheimer disease and related dementias.

Correction

Error in Abstract

Abstract Full Text
free access
JAMA Neurol. 2023;80(9):1004. doi:10.1001/jamaneurol.2023.3271

Error in Author Surname

Abstract Full Text
free access
JAMA Neurol. 2023;80(9):1004. doi:10.1001/jamaneurol.2023.3292
JAMA Neurology Masthead

JAMA Neurology

Abstract Full Text
free access
JAMA Neurol. 2023;80(9):882. doi:10.1001/jamaneurol.2022.4097
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