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October 2017, Vol 74, No. 10, Pages 1157-1271

In This Issue of JAMA Neurology

Highlights

Abstract Full Text
free access
JAMA Neurol. 2017;74(10):1157. doi:10.1001/jamaneurol.2016.4019
Viewpoint

Longitudinal Care for Young Adults With Stroke

Abstract Full Text
JAMA Neurol. 2017;74(10):1163-1164. doi:10.1001/jamaneurol.2017.1874

This Viewpoint discusses a longitudinal care program designed to explore and address unmet needs of stroke survivors.

Hazards of Neurological NomenclatureObservations From Neurodevelopmental and Neurodegenerative Disorders

Abstract Full Text
JAMA Neurol. 2017;74(10):1165-1166. doi:10.1001/jamaneurol.2017.1747

This Viewpoint argues for renaming diseases in a manner that allows an understanding of their underlying mechanisms.

Editorial

Apolipoprotein E ε4 and Risk Factors for Alzheimer Disease—Let’s Talk About Sex

Abstract Full Text
has audio
JAMA Neurol. 2017;74(10):1167-1168. doi:10.1001/jamaneurol.2017.1470

The Expanding Spectrum of Zika Virus Infections of the Nervous System

Abstract Full Text
JAMA Neurol. 2017;74(10):1169-1171. doi:10.1001/jamaneurol.2017.1471

How to Use Blood Pressure Guidelines for Best Cognitive Outcomes

Abstract Full Text
JAMA Neurol. 2017;74(10):1172-1173. doi:10.1001/jamaneurol.2017.1869

Anticoagulation Timing for Atrial Fibrillation in Acute Ischemic StrokeTime to Reopen Pandora’s Box?

Abstract Full Text
JAMA Neurol. 2017;74(10):1174-1175. doi:10.1001/jamaneurol.2017.1919

Neurological Complications of Immunotherapies—Beware of the Checkpoint Ahead

Abstract Full Text
JAMA Neurol. 2017;74(10):1176-1177. doi:10.1001/jamaneurol.2017.1916
Original Investigation

Apolipoprotein E Genotype and Sex Risk Factors for Alzheimer DiseaseA Meta-analysis

Abstract Full Text
free access has audio
JAMA Neurol. 2017;74(10):1178-1189. doi:10.1001/jamaneurol.2017.2188

This meta-analysis determines how sex and APOE genotype affect the risks for developing mild cognitive impairment and Alzheimer disease.

Neurologic Complications Associated With the Zika Virus in Brazilian Adults

Abstract Full Text
has active quiz
JAMA Neurol. 2017;74(10):1190-1198. doi:10.1001/jamaneurol.2017.1703

This cohort study evaluates the rates of acute Zika virus infection among patients hospitalized with Guillain-Barré syndrome, meningoencephalitis, or transverse myelitis.

Association of JNC-8 and SPRINT Systolic Blood Pressure Levels With Cognitive Function and Related Racial Disparity

Abstract Full Text
JAMA Neurol. 2017;74(10):1199-1205. doi:10.1001/jamaneurol.2017.1863

This longitudinal study assesses the long-term outcomes of systolic blood pressure levels recommended by the Eighth Joint National Committee and by the Systolic Blood Pressure Intervention Trial and determines if racial differences exist based on long-term cognitive trajectories.

Rivaroxaban vs Warfarin Sodium in the Ultra-Early Period After Atrial Fibrillation–Related Mild Ischemic StrokeA Randomized Clinical Trial

Abstract Full Text
JAMA Neurol. 2017;74(10):1206-1215. doi:10.1001/jamaneurol.2017.2161

This randomized clinical trial examines whether rivaroxaban or warfarin sodium is safer and more effective for preventing early recurrent stroke in patients with atrial fibrillation–related acute ischemic stroke.

Neurological Complications Associated With Anti–Programmed Death 1 (PD-1) Antibodies

Abstract Full Text
has active quiz
JAMA Neurol. 2017;74(10):1216-1222. doi:10.1001/jamaneurol.2017.1912

This cohort study investigates the frequency, clinical spectrum, and optimum treatment approach to neurological complications associated with anti–PD-1 inhibitor use.

Utility of Combining a Simulation-Based Method With a Lecture-Based Method for Fundoscopy Training in Neurology Residency

Abstract Full Text
has multimedia
JAMA Neurol. 2017;74(10):1223-1227. doi:10.1001/jamaneurol.2017.2073

This education research study evaluates the utility of a simulation-based method vs the traditional lecture-based method for assessment and teaching of fundoscopy to neurology residents.

Neurodevelopmental Disorders Caused by De Novo Variants in KCNB1 Genotypes and Phenotypes

Abstract Full Text
JAMA Neurol. 2017;74(10):1228-1236. doi:10.1001/jamaneurol.2017.1714

This study investigates the clinical spectrum associated with KCNB1 variants and the genotype-phenotype correlations.

Association of Sleep-Disordered Breathing With Cognitive Function and Risk of Cognitive ImpairmentA Systematic Review and Meta-analysis

Abstract Full Text
JAMA Neurol. 2017;74(10):1237-1245. doi:10.1001/jamaneurol.2017.2180

This meta-analysis provides a quantitative synthesis of population-based studies on the relationship between sleep-disordered breathing and risk of cognitive impairment.

Associations Between Midlife Vascular Risk Factors and 25-Year Incident Dementia in the Atherosclerosis Risk in Communities (ARIC) Cohort

Abstract Full Text
JAMA Neurol. 2017;74(10):1246-1254. doi:10.1001/jamaneurol.2017.1658

This study examines Atherosclerosis Risk in Communities (ARIC) cohort participants in midlife and explores associations between midlife vascular risk factors and 25-year dementia incidence in the ARIC Study.

Review

Research Gaps and Controversies in Chronic Traumatic EncephalopathyA Review

Abstract Full Text
JAMA Neurol. 2017;74(10):1255-1262. doi:10.1001/jamaneurol.2017.2396

This review discusses the state of the science of chronic traumatic encephalopathy and raises considerations for researching and interpreting cognitive changes in members of at-risk populations.

JAMA Neurology Clinical Challenge

Multiple Intracranial Parenchymal Lesions Evolving Over a Decade

Abstract Full Text
JAMA Neurol. 2017;74(10):1263-1264. doi:10.1001/jamaneurol.2017.2056

A teenage Chinese girl with intermittent limp and increasing headache was admitted to our the hospital in December 2016. A brain magnetic resonance imaging showed multiple parenchymal lesions, involving the pons, bilateral amygdala, and the left temporal pole. What is your diagnosis?

Research Letter

Noninvasive Vagus Nerve Stimulation for Treatment of Indomethacin-Sensitive Headaches

Abstract Full Text
JAMA Neurol. 2017;74(10):1266-1267. doi:10.1001/jamaneurol.2017.2122

This study examines the effectiveness of transcutaneous stimulation of the vagus nerve for trigeminal autonomic cephalalgias.

Comment & Response

Light Therapy Promoting Dopamine Release by Stimulating Retina in Parkinson Disease

Abstract Full Text
JAMA Neurol. 2017;74(10):1267-1268. doi:10.1001/jamaneurol.2017.1906

Light Therapy Promoting Dopamine Release by Stimulating Retina in Parkinson Disease—Reply

Abstract Full Text
JAMA Neurol. 2017;74(10):1268-1269. doi:10.1001/jamaneurol.2017.1909

Presenting to Primary Stroke Centers or Comprehensive Stroke Centers for Thrombolysis

Abstract Full Text
JAMA Neurol. 2017;74(10):1269. doi:10.1001/jamaneurol.2017.2015

Presenting to Primary Stroke Centers or Comprehensive Stroke Centers for Thrombolysis—Reply

Abstract Full Text
JAMA Neurol. 2017;74(10):1269-1270. doi:10.1001/jamaneurol.2017.2018

Levodopa and Parkinson Disease—Myths Revisited

Abstract Full Text
JAMA Neurol. 2017;74(10):1270. doi:10.1001/jamaneurol.2017.2560

Levodopa and Parkinson Disease—Myths Revisited—Reply

Abstract Full Text
JAMA Neurol. 2017;74(10):1270-1271. doi:10.1001/jamaneurol.2017.2563
Correction

Error in Abstract

Abstract Full Text
free access
JAMA Neurol. 2017;74(10):1271. doi:10.1001/jamaneurol.2017.3044
JAMA Neurology Masthead

JAMA Neurology

Abstract Full Text
free access
JAMA Neurol. 2017;74(10):1160. doi:10.1001/jamaneurol.2016.4020
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