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Although concussion is a common type of traumatic brain injury (around 4 million instances in the United States each year) and most patients recover within a week, a subset of patients experience chronic neuropsychiatric symptoms, such as anxiety and depression, that last for years after the initial injury. In this meta-analysis that included more than 700 000 patients diagnosed with concussion, Fralick and coauthors found a 2-fold higher risk of subsequent suicide compared with those not diagnosed with concussion. Concussion was also associated with a higher risk of suicide attempt and suicidal ideation, suggesting that concussion is indeed associated with an increased risk of suicide. Future studies are required to identify patients at highest risk of suicide and to develop strategies to prevent this devastating outcome. Editorial perspective is provided by Redelmeier and Bhatti.
Highlights. JAMA Neurol. 2019;76(2):129. doi:https://doi.org/10.1001/jamaneurol.2018.2971
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