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Gabor-Mikolos  GLRubin  GM The role of the genome project in determining gene function: insights from model organisms.  Cell. 1996;86521- 529Google ScholarCrossref
Rowen  LMahairas  GHood  L Sequencing the human genome.  Science. 1997;278605- 607Google ScholarCrossref
Collins  F Positional cloning: let's not call it reverse anymore.  Nat Genet. 1992;13- 6Google ScholarCrossref
Selleri  LSmith  MWHolmsen  AL  et al.  High-resolution physical mapping of a 250-kb region of human chromosome 11q24 by genomic sequence sampling (GSS).  Genomics. 1995;26489- 501Google ScholarCrossref
National Center for Biotechnology Information, Not Available. Available at: http://www.ncbi.nlm.nih.gov/
Collins  F Sequencing the human genome.  Hosp Pract (Off Ed). 1997;3235- 4346- 4953- 54Google Scholar
Lawrence  SGiles  CL Searching the World Wide Web.  Science. 1998;28098- 99Google ScholarCrossref
Chalfie  MWhite  J The Nematode Caenorhabditis elegans.  New York, NY CSH Press1988;337- 391
Basic Science Seminars in Neurology
October 1998

The Human Genome Project: Applications in the Diagnosis and Treatment of Neurologic Disease

Author Affiliations

From the McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, Dallas.



Arch Neurol. 1998;55(10):1287-1290. doi:10.1001/archneur.55.10.1287

The Human Genome Project (HGP), an international program to decode the entire DNA sequence of the human genome in 15 years, represents the largest biological experiment ever conducted. This set of information will contain the blueprint for the construction and operation of a human being. While the primary driving force behind the genome project is the potential to vastly expand the amount of genetic information available for biomedical research, the ramifications for other fields of study in biological research, the biotechnology and pharmaceutical industry, our understanding of evolution, effects on agriculture, and implications for bioethics are likely to be profound.