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Observation
March 2003

Right Orbitofrontal Tumor With Pedophilia Symptom and Constructional Apraxia Sign

Author Affiliations

From the Department of Neurology, University of Virginia Health System, Charlottesville.

Arch Neurol. 2003;60(3):437-440. doi:10.1001/archneur.60.3.437
Abstract

Background  Orbitofrontal abnormalities are associated with poor impulse control, altered sexual behavior, and sociopathy.

Objective  To describe a patient with acquired pedophilia and a right orbitofrontal tumor who was unable to inhibit sexual urges despite preserved moral knowledge.

Design  Case report.

Results  The patient displayed impulsive sexual behavior with pedophilia, marked constructional apraxia, and agraphia. The behavioral symptoms and constructional deficits, including agraphia, resolved following tumor resection.

Conclusions  For patients with acquired sociopathy and paraphilia, an orbitofrontal localization requires consideration. This case further illustrates that constructional apraxia can arise from right prefrontal lobe dysfunction. Agraphia may represent a manifestation of constructional apraxia in the absence of aphasia and ideomotor apraxia.

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