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West Nile virus has become a medically important arbovirus in the continental United States with its debut in 1999 in the New York City area. We present neuroimaging features and pathologic findings in 2 patients who were severely affected out of the more that 100 documented cases at our institution. Both patients showed striking involvement of the substantia nigra, a finding not previously reported for West Nile virus.
Bosanko CM, Gilroy J, Wang A, et al. West Nile Virus Encephalitis Involving the Substantia Nigra: Neuroimaging and Pathologic Findings With Literature Review. Arch Neurol. 2003;60(10):1448–1452. doi:10.1001/archneur.60.10.1448
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