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October 2018 - July 1959

Decade

Year

Issue

November 2018, Vol 75, No. 11, Pages 1299-1443

In This Issue of JAMA Neurology

Highlights

Abstract Full Text
free access
JAMA Neurol. 2018;75(11):1299. doi:10.1001/jamaneurol.2017.2666
Viewpoint

Translating Temporal Interference Brain Stimulation to Treat Neurological and Psychiatric Conditions

Abstract Full Text
JAMA Neurol. 2018;75(11):1307-1308. doi:10.1001/jamaneurol.2018.2760

This Viewpoint presents temporal interference stimulation, an optimized alternative to deep brain stimulation, transcranial magnetic stimulation, and transcranial electrical stimulation.

Editorial

Modulation of Nociception in Multiple Brain Systems—The Strain in Pain

Abstract Full Text
JAMA Neurol. 2018;75(11):1309-1310. doi:10.1001/jamaneurol.2018.1752

The Power of Clinical Registries and Quality Improvement CollaborativesGet With The Guidelines–Stroke

Abstract Full Text
JAMA Neurol. 2018;75(11):1311-1312. doi:10.1001/jamaneurol.2018.1853
Original Investigation

Placebo Effects on the Neurologic Pain SignatureA Meta-analysis of Individual Participant Functional Magnetic Resonance Imaging Data

Abstract Full Text
JAMA Neurol. 2018;75(11):1321-1330. doi:10.1001/jamaneurol.2018.2017

This meta-analysis of participant-level data assesses the effect of placebo treatments on pain-associated functional neuroimaging responses in the neurologic pain signature, a multivariate brain pattern tracking nociceptive pain.

Participation in Get With The Guidelines–Stroke and Its Association With Quality of Care for Stroke

Abstract Full Text
JAMA Neurol. 2018;75(11):1331-1337. doi:10.1001/jamaneurol.2018.2101

This longitudinal cohort study compares quality of stroke care measures for patients admitted to hospitals participating and not participating in Get With The Guidelines–Stroke.

Safety and Efficacy of Atorvastatin for Chronic Subdural Hematoma in Chinese PatientsA Randomized ClinicalTrial

Abstract Full Text
has active quiz
JAMA Neurol. 2018;75(11):1338-1346. doi:10.1001/jamaneurol.2018.2030

This randomized clinical trial evaluates the safety and efficacy of atrovastatin as a nonsurgical alternative for treating Chinese patients with chronic subdural hematoma.

Association of Apolipoprotein E ε4 With Transactive Response DNA-Binding Protein 43

Abstract Full Text
has audio
JAMA Neurol. 2018;75(11):1347-1354. doi:10.1001/jamaneurol.2018.3139

This cross-sectional study investigates the association between apolipoprotein E ε4 and transative response DNA-binding protein 43 in US patients with an Alzheimer disease spectrum pathological diagnosis.

Association of MOG-IgG Serostatus With Relapse After Acute Disseminated Encephalomyelitis and Proposed Diagnostic Criteria for MOG-IgG–Associated Disorders

Abstract Full Text
has active quiz
JAMA Neurol. 2018;75(11):1355-1363. doi:10.1001/jamaneurol.2018.1814

This cohort study investigates whether serostatus of autoantibodies targeting myelin oligodendrocyte glycoprotein (transient vs persistent) and titer change over time provide clinical utility in predicting the likelihood of relapse in patients after acute disseminated encephalomyelitis.

Frequency, Predictors, and Outcomes of Prehospital and Early Postarrival Neurological Deterioration in Acute StrokeExploratory Analysis of the FAST-MAG Randomized Clinical Trial

Abstract Full Text
JAMA Neurol. 2018;75(11):1364-1374. doi:10.1001/jamaneurol.2018.1893

This exploratory analysis of 1690 patients enrolled in the Field Administration of Stroke Therapy-Magnesium Trial assesses the frequency, predictors, and outcomes of the neurological deterioration that occurs among patients during the ultra-early period after ischemic stroke or intracranial hemorrhage.

Association Between Midlife Risk Factors and Late-Onset EpilepsyResults From the Atherosclerosis Risk in Communities Study

Abstract Full Text
JAMA Neurol. 2018;75(11):1375-1382. doi:10.1001/jamaneurol.2018.1935

This cohort study examines data from Atherosclerosis Risk in Communities Study to assess the association of midlife vascular and lifestyle risk factors with development of late-onset epilepsy.

Safety and Efficacy of Fludrocortisone in the Treatment of Cerebral Salt Wasting in Patients With Tuberculous MeningitisA Randomized Clinical Trial

Abstract Full Text
JAMA Neurol. 2018;75(11):1383-1391. doi:10.1001/jamaneurol.2018.2178

This randomized clinical trial evaluates the efficacy and safety of fludrocortisone in the treatment of cerebral salt wasting in patients with tuberculous meningitis.

Application of the 2017 Revised McDonald Criteria for Multiple Sclerosis to Patients With a Typical Clinically Isolated Syndrome

Abstract Full Text
JAMA Neurol. 2018;75(11):1392-1398. doi:10.1001/jamaneurol.2018.2160

This study evaluates the diagnostic accuracy of the 2017 McDonald criteria vs the 2010 criteria to predict clinically definite multiple sclerosis in patients with a typical clinically isolated syndrome.

Prevalence of Aging, Dementia, and Multimorbidity in Older Adults With Down Syndrome

Abstract Full Text
JAMA Neurol. 2018;75(11):1399-1406. doi:10.1001/jamaneurol.2018.2210

This study investigates the prevalence of dementia and aging-related comorbidities, such as hypertension, epilepsy, anemia, and weight loss, in older adult individuals with Down syndrome.

Association of Inflammation and Disability Accrual in Patients With Progressive-Onset Multiple Sclerosis

Abstract Full Text
JAMA Neurol. 2018;75(11):1407-1415. doi:10.1001/jamaneurol.2018.2109

This cohort study examines the association of superimposed relapses in progressive-onset multiple sclerosis on disease outcomes.

Brief Report

Frequency of Loss of Function Variants in LRRK2 in Parkinson Disease

Abstract Full Text
JAMA Neurol. 2018;75(11):1416-1422. doi:10.1001/jamaneurol.2018.1885

This case-control cohort study used next-generation sequencing data to determine whether for loss of function variants in LRRK1 and LRRK2 are associated with the etiology of Parkinson disease.

Review

The Emerging Role of Inhaled Heroin in the Opioid EpidemicA Review

Abstract Full Text
JAMA Neurol. 2018;75(11):1423-1434. doi:10.1001/jamaneurol.2018.1693

This narrative review presents the pharmacology, pathophysiology, neuroimaging, and neuropathology of leukoencephalopathy associated with chasing the dragon, a method of heroin usage involving heating the drug and inhaling its fumes.

Images in Neurology

Scalloped Pupil in a Patient With Familial Amyloid Polyneuropathy

Abstract Full Text
JAMA Neurol. 2018;75(11):1435-1436. doi:10.1001/jamaneurol.2018.2075

This case report describes a man in his 40s with ocular manifestations of familial amyloid polyneuropathy.

Association of Transsynaptic Degeneration of the Papez Circuit With Anterior Thalamic Encephalomalacia

Abstract Full Text
JAMA Neurol. 2018;75(11):1437-1438. doi:10.1001/jamaneurol.2018.2262

This case report describes a male adolescent who presented with a history of staring spells and headache for the past 2 years, an abnormal shrieking sound, and a stiffening of the body.

JAMA Neurology Clinical Challenge

Hearing and Vision Loss in an Older Man

Abstract Full Text
JAMA Neurol. 2018;75(11):1439-1440. doi:10.1001/jamaneurol.2018.1868

A 63-year-old with a history of hip arthroplasty with revisions presents to your neurology clinic with bilateral loss of vision and hearing and painful paresthesias at his feet. What is your diagnosis?

Comment & Response

Listeria monocytogenes–Induced Rhombencephalitis—A Paradoxical Disease of Immunocompetent Patients

Abstract Full Text
JAMA Neurol. 2018;75(11):1442. doi:10.1001/jamaneurol.2018.2741

Listeria Monocytogenes–Induced Rhombencephalitis—A Paradoxical Disease of Immunocompetent Patients—Reply

Abstract Full Text
JAMA Neurol. 2018;75(11):1442-1443. doi:10.1001/jamaneurol.2018.2744
Correction

Incorrect Degree

Abstract Full Text
free access
JAMA Neurol. 2018;75(11):1443. doi:10.1001/jamaneurol.2018.2391

Errors in Methods Section

Abstract Full Text
free access
JAMA Neurol. 2018;75(11):1443. doi:10.1001/jamaneurol.2018.3184

Errors in Corresponding Authors Section

Abstract Full Text
free access
JAMA Neurol. 2018;75(11):1443. doi:10.1001/jamaneurol.2018.3623
JAMA Neurology Masthead

JAMA Neurology

Abstract Full Text
free access
JAMA Neurol. 2018;75(11):1303. doi:10.1001/jamaneurol.2017.2667
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