This Viewpoint discusses the validity of using a strategy of targeting no evident disease activity to treat relapsing multiple sclerosis.
This Viewpoint explicates the importance of the circadian system to cluster headaches and proposes this system as a target for drug treatment.
This essay discusses a husband and wife’s recovery from hemineglect.
This meta-analysis examines whether sickle cell trait is associated with a higher risk of incident ischemic stroke among African Americans.
This randomized clinical trial compares pain neuroscience education combined with cognition-targeted motor control training with current best-evidence physiotherapy for reducing pain and improving functionality, gray matter morphologic features, and pain cognitions in individuals with chronic spinal pain.
This cross-sectional study reviews the association of compensated hypercapnia and hypercapnic acidosis during the first 24 hours of intensive care unit admission on hospital mortality in adult mechanically ventilated patients with cerebral injury.
This study investigates the association of progressive multifocal leukoencephalopathy lesion characteristics on magnetic resonance imaging with both qualitative and quantitative John Cunningham virus polymerase chain reaction results in cerebrospinal fluid of patients with natalizumab-associated progressive multifocal leukoencephalopathy.
This randomized clinical trial determine whether stereotactically-guided intracerebral injections of adeno-associated viral vector (serotype 2)-nerve growth factor are well tolerated and exhibit preliminary evidence of impact on cognitive decline in patients with mild to moderate Alzheimer disease with dementia.
This cohort study evaluates the use of preemptive human leukocyte antigen allele HLA-A*31:01 genetic screening to reduce carbamazepine-induced cutaneous adverse drug reactions in a Japanese population.
This predefined subgroup analysis of a randomized clinical trial characterizes cerebral microbleeds in acute intracerebral hemorrhage and assesses the potential for interaction between underlying small vessel disease and assignment to acute intensive blood pressure targeting for functional outcomes and hematoma expansion.
This genome-wide association study examines whether there are common genetic variants that determine risk for amyotrophic lateral sclerosis and other neurodegenerative diseases and identifies novel shared genetic variants and their functional pathways.
This study develops and assesses a smartphone-based measure of Parkinson disease severity, symptom fluctuations, and response to dopaminergic therapy.
This review discusses current acute and preventive pharmacologic therapies for the treatment of migraine in the pediatric and adolescent population.
A 41-year-old man was admitted with acute parkinsonism, which deteriorated over the next few days to a state of akinetic mutism.
This review of interventional neurology trials registered in ClinicalTrials.gov classifies trials and compares publication rates and time to publication between 2007 and 2014.
This cohort study presents serological data with regard to 2 novel glial targets (myelin oligodendrocyte glycoprotein and glial fibrillary acidic protein) in recurrent longitudinally extensive transverse myelitis.