Hall et al assess the ability of 5 biomarkers in 453 cerebrospinal fluid samples in the ability to differentiate between common dementia and parkinsonian disorders. In a related editorial, Perrin discusses why markers for differential diagnosis are important.
Wang and colleagues reported a post-hoc analysis of a randomized aspirincontrolled trial exploring the efficacy and safety of low-molecular-weight heparin (LMWH) for early neurologic deterioration (END) in patients with acute ischemic stroke and large artery occlusive disease.
Olindo et al assess a fluid-attenuated inversion recovery (FLAIR) vascular hyperintensities score and explore its relationship with recanalization status and clinical outcomes after intravenous thrombolysis.
Kim and colleagues studied patients with middle cerebral artery (MCA) territory infarction or transient ischemic attack to evaluate atherosclerosis activity of the MCA by high-resolution magnetic resonance imaging and determine its relationship with infarction patterns.
In a population-based cohort study, Van Gompel et al assess the hypothesis that use of anterior temporal lobectomy for temporal epilepsy has diminished over time.
In a retrospective, cross-sectional cohort study, Qian et al contrast differences in pain and treatment outcomes between neuromyelitis optica and multiple sclerosis.
Siepmann and colleagues conducted a hospital-based study involving 22 healthy volunteers aged 24 to 48 years to quantify piloerection using phenylephrine in humans.
Menke and colleagues studied 21 patients with amyotrophic lateral sclerosis (ALS) and 3 patients with primary lateral sclerosis to explore the value of diffusion tensor imaging applied to those specific cerebral white matter tracts consistently involved pathologically in amyotrophic lateral sclerosis as a source of prognostic biomarkers.
Gokhale et al describe a case and review literature for intracerbral hemorrhage caused by migraine.
Shaw and colleagues describe the clinical, electrographic, and radiographic features of status epilepticus amauroticus, or homonymous hemianopsia associated with partial status epilepticus, in 3 patients with subsequent resolution of radiographic abnormalities and visual deficits.
Gattringer and colleagues conducted a 10-year retrospective case series at a primary and tertiary care university clinic to screen patients with cerebral sinus venous thrombosis for otologic symptoms.
In this review, Costa et al estimate the potential diagnostic added value of the Awaji criteria for diagnosis of amyotrophic lateral sclerosis.
In a randomized, double-blind, placebo-controlled trial, Baker and coauthors examine the effects of growth hormone–releasing hormone on cognitive function in healthy older adults and in adults with mild cognitive impairment.
Coric and coauthors assess the safety, tolerability, and pharmacokinetic and pharmacodynamic effects of the γ-secretase inhibitor avagacestat in patients with mild to moderate Alzheimer disease.