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November 2012, Vol 69, No. 11, Pages 1398-1527

Editorial

Cerebrospinal Fluid Biomarkers for Clinical Trials: Why Markers for Differential Diagnosis Are Important

Abstract Full Text
Arch Neurol. 2012;69(11):1407-1408. doi:10.1001/archneurol.2012.2353
Original Contribution

Accuracy of a Panel of 5 Cerebrospinal Fluid Biomarkers in the Differential Diagnosis of Patients With Dementia and/or Parkinsonian Disorders

Abstract Full Text
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Arch Neurol. 2012;69(11):1445-1452. doi:10.1001/archneurol.2012.1654

Hall et al assess the ability of 5 biomarkers in 453 cerebrospinal fluid samples in the ability to differentiate between common dementia and parkinsonian disorders. In a related editorial, Perrin discusses why markers for differential diagnosis are important.

Low-Molecular-Weight Heparin and Early Neurologic Deterioration in Acute Stroke Caused by Large Artery Occlusive Disease

Abstract Full Text
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Arch Neurol. 2012;69(11):1454-1460. doi:10.1001/archneurol.2012.1633

Wang and colleagues reported a post-hoc analysis of a randomized aspirincontrolled trial exploring the efficacy and safety of low-molecular-weight heparin (LMWH) for early neurologic deterioration (END) in patients with acute ischemic stroke and large artery occlusive disease.

Fluid-Attenuated Inversion Recovery Vascular Hyperintensity: An Early Predictor of Clinical Outcome in Proximal Middle Cerebral Artery Occlusion

Abstract Full Text
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Arch Neurol. 2012;69(11):1462-1468. doi:10.1001/archneurol.2012.1310

Olindo et al assess a fluid-attenuated inversion recovery (FLAIR) vascular hyperintensities score and explore its relationship with recanalization status and clinical outcomes after intravenous thrombolysis.

Middle Cerebral Artery Plaque and Prediction of the Infarction Pattern

Abstract Full Text
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Arch Neurol. 2012;69(11):1470-1475. doi:10.1001/archneurol.2012.1018

Kim and colleagues studied patients with middle cerebral artery (MCA) territory infarction or transient ischemic attack to evaluate atherosclerosis activity of the MCA by high-resolution magnetic resonance imaging and determine its relationship with infarction patterns.

Use of Anterior Temporal Lobectomy for Epilepsy in a Community-Based Population

Abstract Full Text
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Arch Neurol. 2012;69(11):1476-1481. doi:10.1001/archneurol.2012.1200

In a population-based cohort study, Van Gompel et al assess the hypothesis that use of anterior temporal lobectomy for temporal epilepsy has diminished over time.

Association of Neuromyelitis Optica With Severe and Intractable Pain

Abstract Full Text
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Arch Neurol. 2012;69(11):1482-1487. doi:10.1001/archneurol.2012.768

In a retrospective, cross-sectional cohort study, Qian et al contrast differences in pain and treatment outcomes between neuromyelitis optica and multiple sclerosis.

Quantitative Pilomotor Axon Reflex Test: A Novel Test of Pilomotor Function

Abstract Full Text
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Arch Neurol. 2012;69(11):1488-1492. doi:10.1001/archneurol.2012.1092

Siepmann and colleagues conducted a hospital-based study involving 22 healthy volunteers aged 24 to 48 years to quantify piloerection using phenylephrine in humans.

Fractional Anisotropy in the Posterior Limb of the Internal Capsule and Prognosis in Amyotrophic Lateral Sclerosis

Abstract Full Text
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Arch Neurol. 2012;69(11):1493-1498. doi:10.1001/archneurol.2012.1122

Menke and colleagues studied 21 patients with amyotrophic lateral sclerosis (ALS) and 3 patients with primary lateral sclerosis to explore the value of diffusion tensor imaging applied to those specific cerebral white matter tracts consistently involved pathologically in amyotrophic lateral sclerosis as a source of prognostic biomarkers.

Images in Neurology

Schwannoma of the Palmar Cutaneous Nerve: Electrodiagnosis With Radiologic and Pathologic Correlations

Abstract Full Text
Arch Neurol. 2012;69(11):1512. doi:10.1001/archneurol.2012.168

Erdheim-Chester Disease

Abstract Full Text
Arch Neurol. 2012;69(11):1514. doi:10.1001/archneurol.2012.180

Right Eye Droop

Abstract Full Text
Arch Neurol. 2012;69(11):1516. doi:10.1001/archneurol.2012.217
Observation

An Uncommon Cause of Intracerebral Hemorrhage in a Healthy Truck Driver

Abstract Full Text
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Arch Neurol. 2012;69(11):1500-1503. doi:10.1001/archneurol.2011.3753

Gokhale et al describe a case and review literature for intracerbral hemorrhage caused by migraine.

Status Epilepticus Amauroticus Revisited: Ictal and Peri-ictal Homonymous Hemianopsia

Abstract Full Text
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Arch Neurol. 2012;69(11):1504-1507. doi:10.1001/archneurol.2012.317

Shaw and colleagues describe the clinical, electrographic, and radiographic features of status epilepticus amauroticus, or homonymous hemianopsia associated with partial status epilepticus, in 3 patients with subsequent resolution of radiographic abnormalities and visual deficits.

Acute Unilateral Hearing Loss as an Early Symptom of Lateral Cerebral Sinus Venous Thrombosis

Abstract Full Text
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Arch Neurol. 2012;69(11):1508-1511. doi:10.1001/archneurol.2012.346

Gattringer and colleagues conducted a 10-year retrospective case series at a primary and tertiary care university clinic to screen patients with cerebral sinus venous thrombosis for otologic symptoms.

Book Reviews

Atlas of Inherited Metabolic Diseases, 3rd ed

Abstract Full Text
Arch Neurol. 2012;69(11):1521-1522. doi:10.1001/archneurol.2012.2313

Neurocritical Care

Abstract Full Text
Arch Neurol. 2012;69(11):1522. doi:10.1001/archneurol.2012.2316
Obituary

In Memoriam: Robert J. Joynt, MD, PhD (1925-2012)

Abstract Full Text
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Arch Neurol. 2012;69(11):1518-1519. doi:10.1001/archneurol.2012.2265
This Month in Archives of Neurology

This Month in Archives of Neurology

Abstract Full Text
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Arch Neurol. 2012;69(11):1401-1402. doi:10.1001/archneurol.2011.1484
Neurological Review

Awaji Criteria for the Diagnosis of Amyotrophic Lateral Sclerosis: A Systematic Review

Abstract Full Text
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Arch Neurol. 2012;69(11):1410-1416. doi:10.1001/archneurol.2012.254

In this review, Costa et al estimate the potential diagnostic added value of the Awaji criteria for diagnosis of amyotrophic lateral sclerosis.

Clinical Trials

Effects of Growth Hormone–Releasing Hormone on Cognitive Function in Adults With Mild Cognitive Impairment and Healthy Older Adults: Results of a Controlled Trial

Abstract Full Text
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Arch Neurol. 2012;69(11):1420-1429. doi:10.1001/archneurol.2012.1970

In a randomized, double-blind, placebo-controlled trial, Baker and coauthors examine the effects of growth hormone–releasing hormone on cognitive function in healthy older adults and in adults with mild cognitive impairment.

Safety and Tolerability of the γ-Secretase Inhibitor Avagacestat in a Phase 2 Study of Mild to Moderate Alzheimer Disease

Abstract Full Text
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Arch Neurol. 2012;69(11):1430-1440. doi:10.1001/archneurol.2012.2194

Coric and coauthors assess the safety, tolerability, and pharmacokinetic and pharmacodynamic effects of the γ-secretase inhibitor avagacestat in patients with mild to moderate Alzheimer disease.

Correspondence

Prognostic Factors of Acute Partial Transverse Myelitis

Abstract Full Text
Arch Neurol. 2012;69(11):1523-1524. doi:10.1001/archneurol.2012.2302

Prognostic Factors of Acute Partial Transverse Myelitis—Reply

Abstract Full Text
Arch Neurol. 2012;69(11):1523-1524. doi:10.1001/archneurol.2012.2593

Spinocerebellar Ataxia Types 2 and 10: More Than a Coincidental Association?

Abstract Full Text
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Arch Neurol. 2012;69(11):1524-1525. doi:10.1001/archneurol.2012.2281

Spinocerebellar Ataxia Types 2 and 10: More Than a Coincidental Association?—Reply

Abstract Full Text
Arch Neurol. 2012;69(11):1524-1525. doi:10.1001/archneurol.2012.2771

Plasma Anti–Amyloid-β Autoantibodies in All Alzheimer Disease Types

Abstract Full Text
Arch Neurol. 2012;69(11):1525-1527. doi:10.1001/2013.jamaneurol.6

Plasma Anti–Amyloid-β Autoantibodies in All Alzheimer Disease Types—Reply

Abstract Full Text
Arch Neurol. 2012;69(11):1525-1527. doi:10.1001/archneurol.2012.2779

The Evolution of Neurology

Abstract Full Text
Arch Neurol. 2012;69(11):1527. doi:10.1001/archneurol.2012.1257
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