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May 2019 - July 1959

Decade

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Issue

April 2013, Vol 70, No. 4, Pages 430-530

In This Issue of JAMA Neurology

In This Issue of JAMA Neurology

Abstract Full Text
free access
JAMA Neurol. 2013;70(4):434-435. doi:10.1001/jamaneurol.2013.2187
Viewpoint

Outgrowing the Child Neurologist: Facing the Challenges of Transition

Abstract Full Text
JAMA Neurol. 2013;70(4):496-497. doi:10.1001/jamaneurol.2013.1814
Editorial

Pediatric Intracerebral Hemorrhage, Acute Seizures, and Epilepsy

Abstract Full Text
JAMA Neurol. 2013;70(4):437. doi:10.1001/jamaneurol.2013.1801

Contribution of Cerebrovascular Health to the Diagnosis of Alzheimer Disease

Abstract Full Text
JAMA Neurol. 2013;70(4):438-439. doi:10.1001/jamaneurol.2013.1862
Original Contribution

Pediatric Intracerebral Hemorrhage: Acute Symptomatic Seizures and Epilepsy

Abstract Full Text
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JAMA Neurol. 2013;70(4):448-454. doi:10.1001/jamaneurol.2013.1033

To define the incidence of and explore risk factors for seizures and epilepsy in children with spontaneous intracerebral hemorrhage (ICH), Beslow and colleagues conducted a prospective cohort study of 73 pediatric subjects with spontaneous ICH, including 20 perinatal and 53 childhood subjects. Heyer and Roach provide a related editorial.

White Matter Hyperintensities and Cerebral Amyloidosis: Necessary and Sufficient for Clinical Expression of Alzheimer Disease?

Abstract Full Text
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JAMA Neurol. 2013;70(4):455-461. doi:10.1001/jamaneurol.2013.1321

Provenzano and colleagues collected data from the Alzheimer Disease Neuroimaging Initiative public database to determine the impact of white matter hyperintensities (WMHs) and Pittsburgh Compound B positron-emission tomography–derived amyloid positivity on the clinical expression of Alzheimer disease. Karen M. Rodrigue, PhD, provides a related editorial.

Evaluation of Potential Infectivity of Alzheimer and Parkinson Disease Proteins in Recipients of Cadaver-Derived Human Growth Hormone

Abstract Full Text
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JAMA Neurol. 2013;70(4):462-468. doi:10.1001/jamaneurol.2013.1933

Irwin et al examine evidence for human-to-human transmission of Alzheimer disease, Parkinson disease, and related neurodegenerative disease–associated proteins in cadaveric human growth hormone recipients.

Natalizumab Therapy for Highly Active Pediatric Multiple Sclerosis

Abstract Full Text
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JAMA Neurol. 2013;70(4):469-475. doi:10.1001/jamaneurol.2013.923

In a retrospective study, Kornek and coauthors report the use of natalizumab therapy for highly active pediatric multiple sclerosis.

Incidence of Amyotrophic Lateral Sclerosis Among American Indians and Alaska Natives

Abstract Full Text
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JAMA Neurol. 2013;70(4):476-480. doi:10.1001/jamaneurol.2013.929

Autosomal Dominant Spastic Paraplegias: A Review of 89 Families Resulting From a Portuguese Survey

Abstract Full Text
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JAMA Neurol. 2013;70(4):481-487. doi:10.1001/jamaneurol.2013.1956

In a retrospective medical record review, Loureiro et al describe the clinical, genetic, and epidemiological features of Portuguese families with autosomal dominant hereditary spastic paraplegias.

The Aging Brain and Cognition: Contribution of Vascular Injury and Aβ to Mild Cognitive Dysfunction

Abstract Full Text
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JAMA Neurol. 2013;70(4):488-495. doi:10.1001/2013.jamaneurol.405

Marchant and coauthors examine the relationship between neuroimaging measures of vascular brain injury and brain β-amyloid deposition and their associations with cognition in elderly individuals.

Clinical Implications of Basic Neuroscience Research

Cerebrovascular Effects of Apolipoprotein E: Implications for Alzheimer Disease

Abstract Full Text
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JAMA Neurol. 2013;70(4):440-444. doi:10.1001/jamaneurol.2013.2152

Zlokovic reviews β-amyloid–independent and β-amyloid–dependent cerebrovascular effects of apolipoprotein E as well as isoform-specific interactions of apolipoprotein E with low-density lipoprotein receptor-related protein 1 on brain vascular cells.

Clinical Pathologic Conference

Progressive Leg Pain and Weakness

Abstract Full Text
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JAMA Neurol. 2013;70(4):510-514. doi:10.1001/jamaneurol.2013.2158

Navalkele et al describe a man with progressive asymmetric leg pain and weakness, enhancement of the cauda equina and leptomeninges of the lower spinal cord, elevated protein concentration, and lymphocytic pleocytosis. He had normal cytological findings, elevated IgG synthesis, and elevated antibody titers to varicella-zoster virus. Over time, he worsened, developed cranial neuropathies, and died.

Images in Neurology

Fulminant Streptococcal Meningoencephalitis

Abstract Full Text
JAMA Neurol. 2013;70(4):515. doi:10.1001/jamaneurol.2013.1953

Symptomatic Neurocutaneous Melanosis in a Child

Abstract Full Text
JAMA Neurol. 2013;70(4):516. doi:10.1001/jamaneurol.2013.2230

Duret Hemorrhage Following Subdural Hematoma Evacuation

Abstract Full Text
JAMA Neurol. 2013;70(4):518. doi:10.1001/jamaneurol.2013.614

False-Positive Transient Ischemic Attack Due to Intraocular Lesion

Abstract Full Text
JAMA Neurol. 2013;70(4):519. doi:10.1001/jamaneurol.2013.615

Successful Repetitive Intravenous Thrombolysis in a Patient With Recurrent Brainstem Infarctions Due to Megadolichobasilar Ectasia

Abstract Full Text
JAMA Neurol. 2013;70(4):520-521. doi:10.1001/jamaneurol.2013.618
Research Letter

Month of Birth and Thymic Output

Abstract Full Text
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JAMA Neurol. 2013;70(4):527-528. doi:10.1001/jamaneurol.2013.2116
Observation

Progressive Encephalomyelitis With Rigidity and Myoclonus: The First Pediatric Case With Glycine Receptor Antibodies

Abstract Full Text
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JAMA Neurol. 2013;70(4):498-501. doi:10.1001/jamaneurol.2013.1872

Damásio et al describe a pediatric case of progressive encephalomyelitis with rigidity and myoclonus (PERM) with glycine receptor alpha 1 antibodies.

IgG4-Related Neuropathy: A Case Report

Abstract Full Text
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JAMA Neurol. 2013;70(4):502-505. doi:10.1001/jamaneurol.2013.658

Ohyama et al describe the clinical features and nerve biopsy findings of a patient with IgG4-related disease who presented with neuropathy in the extremities.

Patient With Homer-3 Antibodies and Cerebellitis

Abstract Full Text
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JAMA Neurol. 2013;70(4):506-509. doi:10.1001/jamaneurol.2013.1955

Höftberger et al describe the second patient with cerebellitis and Homer-3 antibodies and report a novel, highly specific immunoblot assay.

Book Reviews

Famous First Papers for the Neurointensivist

Abstract Full Text
JAMA Neurol. 2013;70(4):525-526. doi:10.1001/jamaneurol.2013.2217
Obituary

In Memoriam: Robert A. Fishman, MD (1924-2012)

Abstract Full Text
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JAMA Neurol. 2013;70(4):523-524. doi:10.1001/jamaneurol.2013.128
Correspondence

Psychogenic Nonepileptic Seizures: The Name Matters

Abstract Full Text
JAMA Neurol. 2013;70(4):528-529. doi:10.1001/jamaneurol.2013.1467

Psychogenic Nonepileptic Seizures: The Name Matters—Reply

Abstract Full Text
JAMA Neurol. 2013;70(4):528-529. doi:10.1001/jamaneurol.2013.1898

Growth Hormone–Releasing Hormone Improves Cognitive Function in Older Adults: Sleep On It

Abstract Full Text
JAMA Neurol. 2013;70(4):529-530. doi:10.1001/2013.jamaneurol.349

Growth Hormone–Releasing Hormone Improves Cognitive Function in Older Adults: Sleep On It—Reply

Abstract Full Text
JAMA Neurol. 2013;70(4):529-530. doi:10.1001/jamaneurol.2013.2064
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