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April 2019 - July 1959

Decade

Year

Issue

October 2015, Vol 72, No. 10, Pages 1087-1212

In This Issue of JAMA Neurology

Highlights

Abstract Full Text
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JAMA Neurol. 2015;72(10):1087. doi:10.1001/jamaneurol.2014.2871
Editorial

Endovascular Therapy for Acute Ischemic Stroke: Dawn of a New Era

Abstract Full Text
JAMA Neurol. 2015;72(10):1101-1103. doi:10.1001/jamaneurol.2015.1743

Biofluid Biomarkers of Mild Traumatic Brain Injury: Whither Plasma Tau

Abstract Full Text
JAMA Neurol. 2015;72(10):1103-1105. doi:10.1001/jamaneurol.2015.1789

Smoking Beyond Multiple Sclerosis Diagnosis: A Risk Factor Still Worth Modifying

Abstract Full Text
JAMA Neurol. 2015;72(10):1105-1106. doi:10.1001/jamaneurol.2015.1805

Understanding Conflicting Neuropathological Findings in Patients Clinically Diagnosed as Having Alzheimer Dementia

Abstract Full Text
JAMA Neurol. 2015;72(10):1106-1108. doi:10.1001/jamaneurol.2015.1804
Original Investigation

Peripheral Total Tau in Military Personnel Who Sustain Traumatic Brain Injuries During Deployment

Abstract Full Text
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JAMA Neurol. 2015;72(10):1109-1116. doi:10.1001/jamaneurol.2015.1383

This observational study evaluates peripheral tau levels in military personnel exposed to traumatic brain injury and the relationship between elevations in tau and chronic neurological symptoms.

Effect of Smoking Cessation on Multiple Sclerosis Prognosis

Abstract Full Text
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JAMA Neurol. 2015;72(10):1117-1123. doi:10.1001/jamaneurol.2015.1788

This cross-sectional study reports that continued smoking after a diagnosis of multiple sclerosis is associated with an acceleration in time to a secondary-progressive disease course and that those who quit smoking fare better.

Characterizing Apolipoprotein E ε4 Carriers and Noncarriers With the Clinical Diagnosis of Mild to Moderate Alzheimer Dementia and Minimal β-Amyloid Peptide Plaques

Abstract Full Text
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JAMA Neurol. 2015;72(10):1124-1131. doi:10.1001/jamaneurol.2015.1721

This descriptive study compares the neuropathologic changes noted on autopsy of APOE4 carriers and noncarriers who had a diagnosis of mild to moderate Alzheimer dementia with minimal β-amyloid plaques.

Exclusive Breastfeeding and the Effect on Postpartum Multiple Sclerosis Relapses

Abstract Full Text
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JAMA Neurol. 2015;72(10):1132-1138. doi:10.1001/jamaneurol.2015.1806

This cohort study examines the effect of breastfeeding on postpartum relapse in women with multiple sclerosis.

Nerve Growth Factor Gene Therapy: Activation of Neuronal Responses in Alzheimer Disease

Abstract Full Text
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JAMA Neurol. 2015;72(10):1139-1147. doi:10.1001/jamaneurol.2015.1807

This anatomicopathological study presents postmortem findings in 10 patients with early AD who underwent nerve growth factor gene therapy and determines whether degenerating neurons in Alzheimer disease retain an ability to respond to a nervous system growth factor delivered after disease onset.

Intravenous Fibrinolytic Therapy in Central Retinal Artery Occlusion: A Patient-Level Meta-analysis

Abstract Full Text
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JAMA Neurol. 2015;72(10):1148-1154. doi:10.1001/jamaneurol.2015.1578

This patient-level meta-analysis of early systemic fibrinolytic therapy for central retinal artery occlusion compares outcomes in patients receiving conservative therapy, no therapy, and fibrinolytic therapy to determine whether a clinical trial is warranted.

Effect of Presymptomatic Body Mass Index and Consumption of Fat and Alcohol on Amyotrophic Lateral Sclerosis

Abstract Full Text
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JAMA Neurol. 2015;72(10):1155-1162. doi:10.1001/jamaneurol.2015.1584

This case-control study evaluates the association of premorbid body mass index, dietary intake of fat, and alcohol use with amyotrophic lateral sclerosis.

Clinical Spectrum of Encephalitis Associated With Antibodies Against the α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid Receptor: Case Series and Review of the Literature

Abstract Full Text
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JAMA Neurol. 2015;72(10):1163-1169. doi:10.1001/jamaneurol.2015.1715

This case series describes 7 patients with encephalitis with antibodies against the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor and provides a review of the literature on this disease entity.

Clinical Utility of Acetylcholine Receptor Antibody Testing in Ocular Myasthenia Gravis

Abstract Full Text
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JAMA Neurol. 2015;72(10):1170-1174. doi:10.1001/jamaneurol.2015.1444

This cohort study reports a significant association between older age, male sex, and progression to generalized myasthenia gravis and positive acetylcholine receptor antibody test results in patients with ocular myasthenia gravis.

Cerebrospinal Fluid Patterns and the Risk of Future Dementia in Early, Incident Parkinson Disease

Abstract Full Text
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JAMA Neurol. 2015;72(10):1175-1182. doi:10.1001/jamaneurol.2015.1449

This cohort study of idiopathic parkinsonism assesses the diagnostic and prognostic value of a panel of cerebrospinal fluid biomarkers in patients with early Parkinson disease and related disorders.

Comparison of Visual and Quantitative Florbetapir F 18 Positron Emission Tomography Analysis in Predicting Mild Cognitive Impairment Outcomes

Abstract Full Text
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JAMA Neurol. 2015;72(10):1183-1190. doi:10.1001/jamaneurol.2015.1633

This study of diagnostic techniques compares the concordance between visual and quantitative analysis of positron emission tomography for determination of Aβ status in patients with mild cognitive impairment.

Clinical Implications of Basic Neuroscience Research

Blood-Borne Revitalization of the Aged Brain

Abstract Full Text
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JAMA Neurol. 2015;72(10):1191-1194. doi:10.1001/jamaneurol.2015.1616

This article discusses putative mechanisms for blood-borne brain rejuvenation and suggests promising avenues for future research and development of therapies.

Images in Neurology

Progressive Ataxia and Palatal Tremor

Abstract Full Text
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JAMA Neurol. 2015;72(10):1195. doi:10.1001/jamaneurol.2015.1114

This case report describes ataxia with uncontrollable palatal tremor in an elderly man.

Isolated Lingual Dyskinesia in Multiple Sclerosis

Abstract Full Text
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JAMA Neurol. 2015;72(10):1196-1197. doi:10.1001/jamaneurol.2015.1456

This case report describes involuntary lingual dyskinesia with nearly continuous rhythmic movements of the genioglossus in a patient with multiple sclerosis.

Research Letter

Telomere Length Shortening and Alzheimer Disease—A Mendelian Randomization Study

Abstract Full Text
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JAMA Neurol. 2015;72(10):1202-1203. doi:10.1001/jamaneurol.2015.1513

This study explores the causal effect of telomere length on Alzheimer disease by applying the mendelian randomization method to summary genome-wide association study data.

Observation

Cryptococcal Meningoencephalitis in a Patient With Multiple Sclerosis Treated With Fingolimod

Abstract Full Text
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JAMA Neurol. 2015;72(10):1203-1205. doi:10.1001/jamaneurol.2015.1746

This case report discusses a man with relapsing-remitting multiple sclerosis taking fingolimod who presented with throbbing bilateral, retro-orbital and temporal headache, photophobia, and lethargy.

Idiopathic Inflammatory Myopathy Treated With High-Dose Immunoablative Cyclophosphamide—A Long-term Follow-up Study

Abstract Full Text
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JAMA Neurol. 2015;72(10):1205-1206. doi:10.1001/jamaneurol.2015.1425

This long-term case report describes a woman with idiopathic inflammatory myopathy treated with high-dose immunoablative cyclophosphamide.

Wallerian Degeneration of the Superior Cerebellar Peduncle

Abstract Full Text
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JAMA Neurol. 2015;72(10):1206-1208. doi:10.1001/jamaneurol.2015.1170

This case report describes a man who presented with a deep cerebellar hemorrhage with damage to the dentate and interposite nuclei.

Comment & Response

Neuropathy and Celiac Disease—When a Gluten-Free Diet is Not Enough

Abstract Full Text
JAMA Neurol. 2015;72(10):1208-1209. doi:10.1001/jamaneurol.2015.2069

Neuropathy and Celiac Disease—Reply

Abstract Full Text
JAMA Neurol. 2015;72(10):1209. doi:10.1001/jamaneurol.2015.2072

Acceptance of Lesbian, Gay, Bisexual, and Transgender People

Abstract Full Text
JAMA Neurol. 2015;72(10):1209. doi:10.1001/jamaneurol.2015.2128

Acceptance of Lesbian, Gay, Bisexual, and Transgender People—Reply

Abstract Full Text
JAMA Neurol. 2015;72(10):1209-1210. doi:10.1001/jamaneurol.2015.2131
Correction

Second Author Affiliation Missing

Abstract Full Text
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JAMA Neurol. 2015;72(10):1210. doi:10.1001/jamaneurol.2015.2916
Book and Media Review

Review of Bullets and Brains

Abstract Full Text
JAMA Neurol. 2015;72(10):1211. doi:10.1001/jamaneurol.2015.1697

Review of Color Atlas of Neurology

Abstract Full Text
JAMA Neurol. 2015;72(10):1212. doi:10.1001/jamaneurol.2015.1710
JAMA Neurology Masthead

JAMA Neurology

Abstract Full Text
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JAMA Neurol. 2015;72(10):1089. doi:10.1001/jamaneurol.2014.2872
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