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June 2019 - July 1959

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Issue

February 2016, Vol 73, No. 2, Pages 141-247

In This Issue of JAMA Neurology

Highlights

Abstract Full Text
free access
JAMA Neurol. 2016;73(2):141. doi:10.1001/jamaneurol.2015.2437
Viewpoint

Neuroprotection After Traumatic Brain Injury

Abstract Full Text
JAMA Neurol. 2016;73(2):149-150. doi:10.1001/jamaneurol.2015.3627

This Viewpoint discusses the role of animal studies in clinical trials of neuroprotection in traumatic brain injury.

Neurology Advocacy 2.0: After Sustainable Growth Rate Repeal

Abstract Full Text
JAMA Neurol. 2016;73(2):151-152. doi:10.1001/jamaneurol.2015.2666

This Viewpoint examines the reforms needed in the field of neurology after the repeal of the sustainable growth rate.

Editorial

Switched On—Expert Advice in Prehospital Thrombolysis via Telemedicine

Abstract Full Text
JAMA Neurol. 2016;73(2):153-154. doi:10.1001/jamaneurol.2015.3875

Emergency Reversal of Novel Oral Anticoagulants: Help Is on the Way

Abstract Full Text
JAMA Neurol. 2016;73(2):155-156. doi:10.1001/jamaneurol.2015.3884

The High Risk of Low Distal Flow

Abstract Full Text
JAMA Neurol. 2016;73(2):157-158. doi:10.1001/jamaneurol.2015.3885
Original Investigation

Telemedicine in Prehospital Stroke Evaluation and Thrombolysis: Taking Stroke Treatment to the Doorstep

Abstract Full Text
free access
JAMA Neurol. 2016;73(2):162-168. doi:10.1001/jamaneurol.2015.3849

This observational study tested whether telemedicine is reliable and remote physician presence adequate for acute stroke treatment using a mobile stroke treatment unit.

Early Clinical and Radiological Course, Management, and Outcome of Intracerebral Hemorrhage Related to New Oral Anticoagulants

Abstract Full Text
free access
JAMA Neurol. 2016;73(2):169-177. doi:10.1001/jamaneurol.2015.3682

This multicenter observational study evaluated the early clinical and radiological course, acute management, and outcome of intracerebral hemorrhage related to non–vitamin K antagonist oral anticoagulant use.

Effect of Hemodynamics on Stroke Risk in Symptomatic Atherosclerotic Vertebrobasilar Occlusive Disease

Abstract Full Text
free access
JAMA Neurol. 2016;73(2):178-185. doi:10.1001/jamaneurol.2015.3772

This longitudinal cohort study evaluates the risk for posterior circulation stroke in patients with symptomatic occlusive disease of the vertebrobasilar system.

Definition and Implications of the Preventable Stroke

Abstract Full Text
free access
JAMA Neurol. 2016;73(2):186-189. doi:10.1001/jamaneurol.2015.3587

This study tests whether most patients with acute stroke exhibited some degree of stroke preventability.

Clinical Trial

Time to Reperfusion and Treatment Effect for Acute Ischemic Stroke: A Randomized Clinical Trial

Abstract Full Text
free access
JAMA Neurol. 2016;73(2):190-196. doi:10.1001/jamaneurol.2015.3886

This randomized clinical trial evaluates the influence of time from stroke onset to the start of treatment and from onset to reperfusion on the effect of intra-arterial treatment in a population of patients with acute ischemic stroke.

Validation of Clinicoradiological Criteria for the Diagnosis of Cerebral Amyloid Angiopathy–Related Inflammation

Abstract Full Text
free access
JAMA Neurol. 2016;73(2):197-202. doi:10.1001/jamaneurol.2015.4078

This study assesses the sensitivity and specificity of clinical and neuroimaging-based criteria for diagnosing cerebral amyloid angiopathy–related inflammation in cases and controls.

Combined Plasma and Cerebrospinal Fluid Signature for the Prediction of Midterm Progression From Mild Cognitive Impairment to Alzheimer Disease

Abstract Full Text
free access
JAMA Neurol. 2016;73(2):203-212. doi:10.1001/jamaneurol.2015.3135

This cohort study combines diverse patient variables from the Alzheimer’s Disease Neuroimaging Initiative database to optimize prediction of midterm progression from mild cognitive impairment to Alzheimer disease dementia.

Variability of Brain Death Policies in the United States

Abstract Full Text
free access
JAMA Neurol. 2016;73(2):213-218. doi:10.1001/jamaneurol.2015.3943

This study evaluates whether hospitals have adopted the 2010 guidelines on the determination of brain death from the American Academy of Neurology and whether policy changes have taken place.

Review

Effect of Multiple Sclerosis Disease-Modifying Therapies on B Cells and Humoral Immunity

Abstract Full Text
JAMA Neurol. 2016;73(2):219-225. doi:10.1001/jamaneurol.2015.3977

This review examines the effects of multiple sclerosis disease-modifying therapies on B-cell immunity.

Clinical Pathologic Conference

Rapid Multifocal Neurologic Decline in an Immunocompromised Patient

Abstract Full Text
free access
JAMA Neurol. 2016;73(2):226-231. doi:10.1001/jamaneurol.2015.2658

This clinical pathologic conference report discusses the clinical approach and neuropathological findings in a 72-year-old man who presented with progressive multifocal neurologic decline after receiving a diagnosis of chronic lymphocytic leukemia.

Images in Neurology

Reversible Cerebral Vasoconstriction Syndrome

Abstract Full Text
JAMA Neurol. 2016;73(2):232-233. doi:10.1001/jamaneurol.2015.3472

This case report describes a woman in her 30s with a generalized tonic-clonic seizure after synthetic cannabis use.

Striking Central Pontine Myelinolysis in a Patient With Alcohol Dependence Syndrome Without Hyponatremia

Abstract Full Text
JAMA Neurol. 2016;73(2):234-235. doi:10.1001/jamaneurol.2015.2201

This case report describes of a man in his 70s with known alcohol dependence syndrome whose neuroimaging revealed a striking triangular central pontine defect in keeping with central pontine myelinolysis.

Research Letter

Expanding Phenotypic Spectrum of NKX2-1–Related Disorders—Mitochondrial and Immunologic Dysfunction

Abstract Full Text
free access
JAMA Neurol. 2016;73(2):237-238. doi:10.1001/jamaneurol.2015.2976

This case series describes 2 members of a family who had a novel NKX2-1 mutation associated with reduction of muscle mitochondrial respiratory chain complex activity and recurrent meningitis.

Comment & Response

Varicella-Zoster Virus in Giant Cell Arteritis

Abstract Full Text
JAMA Neurol. 2016;73(2):238-239. doi:10.1001/jamaneurol.2015.3868

Varicella-Zoster Virus in Giant Cell Arteritis—Reply

Abstract Full Text
JAMA Neurol. 2016;73(2):239. doi:10.1001/jamaneurol.2015.3871

Confounders Regarding the Association of Insulin Resistance and Alzheimer Disease

Abstract Full Text
JAMA Neurol. 2016;73(2):239-240. doi:10.1001/jamaneurol.2015.3983

Confounders Regarding the Association of Insulin Resistance and Alzheimer Disease—Reply

Abstract Full Text
JAMA Neurol. 2016;73(2):240-241. doi:10.1001/jamaneurol.2015.3986

Clonic Perseveration vs Stereotypy Phenomenology

Abstract Full Text
JAMA Neurol. 2016;73(2):241. doi:10.1001/jamaneurol.2015.3921

Clonic Perseveration vs Stereotypy Phenomenology—Reply

Abstract Full Text
JAMA Neurol. 2016;73(2):241-242. doi:10.1001/jamaneurol.2015.3926
Correction

Error in Author’s Name

Abstract Full Text
free access
JAMA Neurol. 2016;73(2):242. doi:10.1001/jamaneurol.2015.4958
Obituary

In Memoriam: Oliver Sacks, MD (July 9, 1933, to August 30, 2015)

Abstract Full Text
free access
JAMA Neurol. 2016;73(2):246-247. doi:10.1001/jamaneurol.2015.3887
JAMA Neurology Masthead

JAMA Neurology

Abstract Full Text
free access
JAMA Neurol. 2016;73(2):143. doi:10.1001/jamaneurol.2015.2438
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