This Viewpoint assesses the frequency of next-generation sequencing use among neurologists and identifies barriers in its implementation.
This cross-sectional study assesses the variability of disease severity in a large cohort of children and adolescents with Charcot-Marie-Tooth disease.
This study reports 7 cases of severe myasthenia gravis treated with autologous hematopoietic stem cell transplant in which consistent, durable, symptom-free, and treatment-free remission was achieved.
This double-blind, cross-over study of carbamazepine in 2 patients with inherited erythromelalgia aims to determine whether pain can be attenuated via pharmacotherapy guided by genomic analysis and functional profiling.
This cohort study describes the phenotype, genetic etiology, and investigation of extrapyramidal movement disorders in pediatric and adult patients with mitochondrial disease.
This meta-analysis investigates the association of high cerebral microbleed burden with the risk of symptomatic intracerebral hemorrhage in patients with acute ischemic stroke treated with intravenous thrombolysis.
This case-control study compares the longitudinal rate and pattern of intraepidermal nerve fiber density change in idiopathic small fiber neuropathy (SFN), impaired glucose tolerance–associated SFN, and diabetes mellitus–associated SFN.
This genetic epidemiology study examines whether there is an association between genetic traits for immune-mediated diseases that promote inflammation and Alzheimer disease.
This cohort study of 4 hypothetical preclinical Alzheimer disease groups identifies which group of cognitively normal individuals shows the greatest cognitive decline over time based on their cerebrospinal fluid biomarker profile.
This observational study examines long-term outcomes in patients with anti-N-methyl-d-aspartate receptor encephalitis.
This case-series study reports the clinical and immunologic findings in a cohort of patients with stiff-person spectrum disorder, including stiff-person syndrome, stiff-limb syndrome, or stiff-person syndrome plus progressive encephalomyelitis with rigidity, myoclonus, or other symptoms.
This study assesses the association between anticholinergic medication use and cognition, glucose metabolism, and brain atrophy in cognitively normal older adults from the Alzheimer’s Disease Neuroimaging Initiative and the Indiana Memory and Aging Study.
This clinical-pathological study characterizes the neurological, cognitive, and neuroimaging features of patients with nonfluent/agrammatic primary progressive aphasia—in whom either progressive supranuclear palsy or corticobasal degeneration was eventually confirmed at autopsy—at initial presentation and at 1-year follow-up and identifies features associated with underlying pathology.
This narrative review assesses a proposed new diagnostic construct for the clinical syndrome associated with repetitive exposure to head impact trauma to provide a clinical framework for the diagnosis of traumatic encephalopathy syndrome.
This case report describes a woman in her 70s with a history of atrial fibrillation who presented with slurred speech and difficulty ambulating for 1 hour.
A 24-year-old woman had a strong unilateral headache located in her left cheek, eye, and forehead that evolved during the evening hours, peaked at night, and decreased again until the morning, without any remarkable trigger along with ipsilateral lacrimation, a red eye, and periorbital swelling but without ptosis. What is your diagnosis?
This study administered noxious mechanical stimuli to individuals with congenital insensitivity to pain and sampled their brain activity with functional magnetic resonance imaging.
This case report describes a case of fulminant central nervous system nocardiosis at 5 months after initiation of alemtuzumab in a patient with multiple sclerosis.
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