This randomized clinical trial compares focused ultrasound thalamotomy with sham treatment for relieving tremor in patients with medication-refractory, tremor-dominant Parkinson disease.
This study use seizure risk factors from electroencephalography and clinical history to create a simple scoring system for predicting the probability of seizures in patients with acute illness.
This population-based, case-control, family aggregation study examines the frequency and range of neuropsychiatric conditions that occur within individual first-degree and second-degree relatives of patients with amyotrophic lateral sclerosis.
This population-based cohort study from the Rotterdam Study evaluates the association between cognitive function and risk of parkinsonism or Parkinson disease in participants who were free of parkinsonism and dementia.
This population-based cohort study evaluates the long-term effects of stroke on functional ability in patients before and after stroke compared with before and after myocardial infarction.
This longitudinal cohort study assesses peripheral inflammatory markers, tracks immune changes, and correlates these changes with disease progression in patients with amyotrophic lateral sclerosis.
This imaging substudy of the Harvard Aging Brain Study examined associations between subjective cognitive decline and global β-amyloid and tau burdens in regions of interest in clinically healthy older adults.
This time course study using 1035 mice seeks to define consistent measures of disease in a transgenic mouse model that could be implemented by drug discovery programs for in vivo compound evaluation.
This cohort study uses data from the Religious Orders Study and the Rush Memory and Aging Project to investigate the association between brain gene expression, DNA methylation, and alteration of magnetic resonance imaging transverse relaxation in late-life cognitive decline.
This cohort modelling study constructs biomarker-based prognostic models that enable determination of future Alzheimer disease dementia in patients with mild cognitive impairment.
This cohort study compared the performance of amyloid positron emission tomography and 5 β-amyloid cerebrospinal fluid assays for detecting amyloid deposition in the brains of patients with mild cognitive complaints.
This study presents a genetic locus for intracranial arachnoid cysts.
A 30-year-old woman with a remote history of Hemophilus influenzae type b meningitis causing quadraparesis was admitted to the hospital with Candida fungemia.
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