This Viewpoint discusses recent changes in the ownership of deflazacort, a drug important in the treatment of Duchenne muscular dystrophy, and advocates for fairer pricing.
This Viewpoint examines the use of tocilizumab as glucocorticoid-sparing treatment in patients with giant cell arteritis.
This Viewpoint describes the results of 5 randomized clinical trials of devices that occlude patent foramen ovale, discusses the cerebrovascular outcomes associated with treatment, and outlines judicious use of closure procedures.
This On the Brain article looks at Mary Shelley’s classic work Frankenstein in film adaptations and spin-offs.
This population-based cohort and Norwegian biobank study examines the association of folic acid supplements and maternal folate concentration in pregnancy with the frequency and degree of autistic traits in children exposed to antiepileptic drugs in utero.
This randomized clinical trial evaluates the safety and potential symptomatic effects of deep brain stimulation of the nucleus basalis of Meynert in patients with Parkinson disease dementia.
This study evaluates the relationship between bone mineral density and intracranial aneurysm.
This randomized clinical trial evaluates the effect of 5, 50, 120, and 300 mg galcanezumab vs placebo as prophylaxis for patients with migraine.
This case series identifies cortical control sites for human blood pressure regulation in humans.
This study explores the frequency of intracranial atherosclerotic disease in patients who have had a stroke and whether it coexists with systemic atherosclerotic lesions and other stroke etiologies.
This population-based study evaluates the association between blood pressure declines and microinfarcts found on autopsy in participants in the Mayo Clinic Study on Aging.
This phase 2 randomized clinical trial examines the feasibility and safety of high-intensity treadmill exercise in patients with de novo Parkinson disease who are not taking medication and whether the effect on the motor system warrants a phase 3 trial.
This case-control study evaluates the associations between β-amyloid, tau pathology, and cognition by comparing cognitively normal and mildly cognitively impaired patients with Parkinson disease with healthy control participants.
This multicenter cross-sectional study assesses the occurrence of cognitive, structural, and microstructural changes in presymptomatic carriers of C9orf72 mutation.
This review reports the ablative and nonablative applications of transcranial focused ultrasound for neurological conditions.
This case reports describes Pisa syndrome in a child with subacute sclerosing panencephalitis.
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