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October 2021 - July 1959

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Issue

March 2018, Vol 75, No. 3, Pages 265-384

In This Issue of JAMA Neurology

Highlights

Abstract Full Text
free access
JAMA Neurol. 2018;75(3):265. doi:10.1001/jamaneurol.2017.2626
Viewpoint

Neuromedicine Service and Science Hub Model

Abstract Full Text
JAMA Neurol. 2018;75(3):271-272. doi:10.1001/jamaneurol.2017.3976

This Viewpoint describes an interdisciplinary service and science hub specialty care model.

Editorial

Questioning the Effectiveness of Newer Antiseizure Medications

Abstract Full Text
JAMA Neurol. 2018;75(3):273-274. doi:10.1001/jamaneurol.2017.3069

Valuable Insights Into Visual Neuroplasticity After Optic Neuritis

Abstract Full Text
JAMA Neurol. 2018;75(3):274-276. doi:10.1001/jamaneurol.2017.3065

Thrombectomy Options for Acute Ischemic Stroke: Which Way to Go?

Abstract Full Text
JAMA Neurol. 2018;75(3):276-278. doi:10.1001/jamaneurol.2017.3985
Original Investigation

Treatment Outcomes in Patients With Newly Diagnosed Epilepsy Treated With Established and New Antiepileptic Drugs: A 30-Year Longitudinal Cohort Study

Abstract Full Text
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JAMA Neurol. 2018;75(3):279-286. doi:10.1001/jamaneurol.2017.3949

This longitudinal cohort study assessed treatment outcomes in patients with newly diagnosed epilepsy and calculated the probability of achieving seizure freedom with first, second, and successive drug regimens prescribed.

Anatomical Wiring and Functional Networking Changes in the Visual System Following Optic Neuritis

Abstract Full Text
free access
JAMA Neurol. 2018;75(3):287-295. doi:10.1001/jamaneurol.2017.3880

This study examines the anatomical and functional visual networks in patients with clinically isolated syndrome optic neuritis.

Association of Visual Impairment in Neuromyelitis Optica Spectrum Disorder With Visual Network Reorganization

Abstract Full Text
free access
JAMA Neurol. 2018;75(3):296-303. doi:10.1001/jamaneurol.2017.3890

This cross-sectional study examines adaptive visual network connectivity changes in neuromyelitis optica spectrum disorder.

Safety and Efficacy of a 3-Dimensional Stent Retriever With Aspiration-Based Thrombectomy vs Aspiration-Based Thrombectomy Alone in Acute Ischemic Stroke Intervention: A Randomized Clinical Trial

Abstract Full Text
free access
JAMA Neurol. 2018;75(3):304-311. doi:10.1001/jamaneurol.2017.3967

This randomized clinical noninferiority trial assesses a novel 3-dimensional stent retriever when used in conjunction with aspiration-based mechanical thrombectomy compared with aspiration-based mechanical thrombectomy alone in patients with acute ischemic stroke.

Progression in the LRRK2-Associated Parkinson Disease Population

Abstract Full Text
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JAMA Neurol. 2018;75(3):312-319. doi:10.1001/jamaneurol.2017.4019

This longitudinal study examines whether the course of Parkinson disease in patients with the LRRK2 mutation differs from the course of Parkinson disease in patients without the mutation.

Comparative Effectiveness of Rituximab and Other Initial Treatment Choices for Multiple Sclerosis

Abstract Full Text
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JAMA Neurol. 2018;75(3):320-327. doi:10.1001/jamaneurol.2017.4011

This observational cohort study assesses the effectiveness and drug discontinuation rates of rituximab among patients with newly diagnosed relapsing-remitting multiple sclerosis compared with injectable disease-modifying treatments, dimethyl fumarate, fingolimod, or natalizumab.

Associations of the Top 20 Alzheimer Disease Risk Variants With Brain Amyloidosis

Abstract Full Text
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JAMA Neurol. 2018;75(3):328-341. doi:10.1001/jamaneurol.2017.4198

This study investigates the association of the top 20 Alzheimer disease risk variants with brain amyloidosis.

Rates of Amyloid Imaging Positivity in Patients With Primary Progressive Aphasia

Abstract Full Text
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JAMA Neurol. 2018;75(3):342-352. doi:10.1001/jamaneurol.2017.4309

This prospective case series examines the rates of positron emission tomography amyloid positivity in the main clinical variants of primary progressive aphasia.

Efficacy and Safety of Deep Brain Stimulation in Tourette Syndrome: The International Tourette Syndrome Deep Brain Stimulation Public Database and Registry

Abstract Full Text
free access
JAMA Neurol. 2018;75(3):353-359. doi:10.1001/jamaneurol.2017.4317

This study uses patients in the International Deep Brain Stimulation Database and Registry to assess the efficacy and safety of deep brain stimulation in a multinational cohort of patients with Tourette syndrome.

Association of Polygenic Risk Score With Cognitive Decline and Motor Progression in Parkinson Disease

Abstract Full Text
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JAMA Neurol. 2018;75(3):360-366. doi:10.1001/jamaneurol.2017.4206

This population-based study investigates the cumulative association of established genetic risk factors for Parkinson disease with cognitive impairment and reexamines the association of the polygenetic risk score with motor progression and survival among patients with Parkinson disease.

Review

Globus Pallidus Interna or Subthalamic Nucleus Deep Brain Stimulation for Parkinson Disease: A Review

Abstract Full Text
JAMA Neurol. 2018;75(3):367-372. doi:10.1001/jamaneurol.2017.4321

This review discusses the benefits and risks to be considered in selection of deep brain stimulation of the subthalamic nucleus or globus pallidus interna in patients with Parkinson disease.

Images in Neurology

Atypical Cause of “Typical” Hypertensive Intracranial Bleeding

Abstract Full Text
JAMA Neurol. 2018;75(3):373. doi:10.1001/jamaneurol.2017.4099

This case report describes an atypical cause of hypertensive intracranial bleeding.

Serial Magnetic Resonance Imaging Changes in a Patient With Late-Onset Cobalamin C Disease With a Misdiagnosis of Metachromatic Leukodystrophy

Abstract Full Text
JAMA Neurol. 2018;75(3):374-375. doi:10.1001/jamaneurol.2017.4527

This case report stresses the importance of recognizing cobalamin C disease in patients with leukoencephalopathies.

JAMA Neurology Clinical Challenge

Evolution of Unilateral Basal Ganglia Lesion Over 16 Months

Abstract Full Text
JAMA Neurol. 2018;75(3):376-377. doi:10.1001/jamaneurol.2017.4875

An adolescent boy presented with cognitive and behavioral changes, headaches, and progressively worsening weakness of the left arm and leg. On magnetic resonance imaging, a lesion in the right basal ganglia discovered 16 months previously appeared larger. What is your diagnosis?

Research Letter

Enoxaparin vs Aspirin in Patients With Cancer and Ischemic Stroke: The TEACH Pilot Randomized Clinical Trial

Abstract Full Text
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JAMA Neurol. 2018;75(3):379-381. doi:10.1001/jamaneurol.2017.4211

This randomized clinical trial compares anticoagulation vs antiplatelet therapy in patients with cancer and acute ischemic stroke.

Comment & Response

Tau in Chronic Traumatic Encephalopathy

Abstract Full Text
JAMA Neurol. 2018;75(3):381. doi:10.1001/jamaneurol.2017.4890

Tau in Chronic Traumatic Encephalopathy—Reply

Abstract Full Text
JAMA Neurol. 2018;75(3):381-382. doi:10.1001/jamaneurol.2017.4893

Future of Neurologic Examination in Clinical Practice

Abstract Full Text
JAMA Neurol. 2018;75(3):382. doi:10.1001/jamaneurol.2017.4995

Future of Neurologic Examination in Clinical Practice

Abstract Full Text
JAMA Neurol. 2018;75(3):383. doi:10.1001/jamaneurol.2017.4998

Future of Neurologic Examination in Clinical Practice

Abstract Full Text
JAMA Neurol. 2018;75(3):383-384. doi:10.1001/jamaneurol.2017.5001

Future of Neurologic Examination in Clinical Practice—Reply

Abstract Full Text
JAMA Neurol. 2018;75(3):384. doi:10.1001/jamaneurol.2017.5004
Correction

Incorrect Terminology

Abstract Full Text
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JAMA Neurol. 2018;75(3):384. doi:10.1001/jamaneurol.2017.4500

Errors in Abstract and Figures 2 and 3

Abstract Full Text
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JAMA Neurol. 2018;75(3):384. doi:10.1001/jamaneurol.2017.4512

Error in Data Presentation

Abstract Full Text
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JAMA Neurol. 2018;75(3):384. doi:10.1001/jamaneurol.2018.0018

Error in Abstract

Abstract Full Text
free access
JAMA Neurol. 2018;75(3):384. doi:10.1001/jamaneurol.2018.0060

Errors in Author Affiliations and Missing Degree

Abstract Full Text
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JAMA Neurol. 2018;75(3):384. doi:10.1001/jamaneurol.2018.0308
JAMA Neurology Masthead

JAMA Neurology

Abstract Full Text
free access
JAMA Neurol. 2018;75(3):267. doi:10.1001/jamaneurol.2017.2627
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