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September 2019 - July 1959

Decade

Year

Issue

August 2018, Vol 75, No. 8, Pages 903-1028

In This Issue of JAMA Neurology

Highlights

Abstract Full Text
free access
JAMA Neurol. 2018;75(8):903. doi:10.1001/jamaneurol.2017.2651
Viewpoint

Anti–Myelin Oligodendrocyte Glycoprotein Antibody–Associated Central Nervous System Demyelination—A Novel Disease Entity?

Abstract Full Text
JAMA Neurol. 2018;75(8):909-910. doi:10.1001/jamaneurol.2018.1055

This Viewpoint summarizes the current knowledge of the clinical, radiologic, and immunologic features of adult patients who are positive for anti–myelin oligodendrocyte glycoprotein and compares these individuals with patients with multiple sclerosis and patients with neuromyelitis optica.

On the Brain

Five Questions That Every Patient Has but Never Asks

Abstract Full Text
JAMA Neurol. 2018;75(8):911-912. doi:10.1001/jamaneurol.2018.1743

This essay describes a clinician’s insights after a personal conversation with a new patient about the questions that most patients do not ask.

Editorial

Deaths in Epilepsy: What We Are Missing

Abstract Full Text
JAMA Neurol. 2018;75(8):913-915. doi:10.1001/jamaneurol.2018.0002

What’s Next (Generation) for the Diagnosis of Chronic Meningitis?

Abstract Full Text
JAMA Neurol. 2018;75(8):915-917. doi:10.1001/jamaneurol.2018.0473

Discovering New Benefits From Old Drugs With Big Data—Promise for Parkinson Disease

Abstract Full Text
JAMA Neurol. 2018;75(8):917-920. doi:10.1001/jamaneurol.2018.0345

Closing the Sex Divide in the Emerging Field of Neurology

Abstract Full Text
JAMA Neurol. 2018;75(8):920-921. doi:10.1001/jamaneurol.2018.0300
Original Investigation

Risk of Unnatural Mortality in People With Epilepsy

Abstract Full Text
free access has active quiz
JAMA Neurol. 2018;75(8):929-938. doi:10.1001/jamaneurol.2018.0333

This population-based cohort study uses 2 large electronic primary care data sets linked to hospitalization and mortality records in England and Wales to estimate cause-specific unnatural mortality risks in people with epilepsy and to identify the medication types involved in poisoning deaths.

Anti–Tumor Necrosis Factor Therapy and Incidence of Parkinson Disease Among Patients With Inflammatory Bowel Disease

Abstract Full Text
free access
JAMA Neurol. 2018;75(8):939-946. doi:10.1001/jamaneurol.2018.0605

This cohort study uses 2 large administrative claims databases to examine the incidence of Parkinson disease among patients with inflammatory bowel disease and to assess whether exposure to antitumor necrosis factor therapy among these patients mitigates Parkinson disease risk.

Chronic Meningitis Investigated via Metagenomic Next-Generation Sequencing

Abstract Full Text
open access
JAMA Neurol. 2018;75(8):947-955. doi:10.1001/jamaneurol.2018.0463

This case series of 7 participants assesses whether metagenomic next-generation sequencing of cerebrospinal fluid can be leveraged to aid in determining diagnoses among patients with subacute or chronic meningitis.

Sex Differences in Academic Rank and Publication Rate at Top-Ranked US Neurology Programs

Abstract Full Text
free access has active quiz
JAMA Neurol. 2018;75(8):956-961. doi:10.1001/jamaneurol.2018.0275

This cross-sectional study investigates the potential sex differences at each faculty rank in top-ranked US academic neurology programs by comparing the number of male vs female neurologists and their level of academic productivity quantitated by publication rates and scholarly activities.

Fertility and Birth Outcomes in Women With Epilepsy Seeking Pregnancy

Abstract Full Text
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JAMA Neurol. 2018;75(8):962-969. doi:10.1001/jamaneurol.2018.0646

This multicenter cohort study aims to determine if women with epilepsy without a prior diagnosis of infertility or related disorders are as likely to achieve pregnancy within 12 months as their peers without epilepsy.

Prevalence and Outcomes of Amyloid Positivity Among Persons Without Dementia in a Longitudinal, Population-Based Setting

Abstract Full Text
free access
JAMA Neurol. 2018;75(8):970-979. doi:10.1001/jamaneurol.2018.0629

This population-based study assesses the prevalence and outcomes of amyloid positivity in a large population of individuals who are cognitively unimpaired or have mild cognitive impairment.

Chemotherapy-Induced Peripheral Neuropathy in Long-term Survivors of Childhood Cancer: Clinical, Neurophysiological, Functional, and Patient-Reported Outcomes

Abstract Full Text
free access
JAMA Neurol. 2018;75(8):980-988. doi:10.1001/jamaneurol.2018.0963

This cross-sectional study comprehensively assesses chemotherapy-induced peripheral neuropathy in childhood cancer survivors to define disease burden and functional effect and aims to inform screening recommendations.

Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau

Abstract Full Text
free access
JAMA Neurol. 2018;75(8):989-998. doi:10.1001/jamaneurol.2018.0821

This multicohort study evaluates sex differences in the association between APOE and markers of Alzheimer disease neuropathology measured in cerebrospinal fluid during life or in brain tissue at autopsy.

Assessment of Extent and Role of Tau in Subcortical Vascular Cognitive Impairment Using 18F-AV1451 Positron Emission Tomography Imaging

Abstract Full Text
free access
JAMA Neurol. 2018;75(8):999-1007. doi:10.1001/jamaneurol.2018.0975

This cross-sectional study investigates the extent and the role of tau in patients with subcortical vascular cognitive impairment using 18F-AV1451, which is a new ligand to detect neurofibrillary tangles in vivo.

Brief Report

A Histologic Study of the Circadian System in Parkinson Disease, Multiple System Atrophy, and Progressive Supranuclear Palsy

Abstract Full Text
JAMA Neurol. 2018;75(8):1008-1012. doi:10.1001/jamaneurol.2018.0640

This brain bank case-control study analyzes disease-specific inclusions in the key structures of the circadian system in patients with Parkinson disease, multiple system atrophy, and progressive supranuclear palsy.

Review

Use of Vitamins and Dietary Supplements by Patients With Multiple Sclerosis: A Review

Abstract Full Text
JAMA Neurol. 2018;75(8):1013-1021. doi:10.1001/jamaneurol.2018.0611

This review discusses the current state of evidence for the role that vitamins and dietary supplements play in multiple sclerosis and its animal models, with an emphasis on recent studies, and addresses biological plausibility and safety issues.

Images in Neurology

Cerebral Embolus From Aortic Valve Fragment

Abstract Full Text
JAMA Neurol. 2018;75(8):1022-1023. doi:10.1001/jamaneurol.2018.1178

This case report describes an African American woman in her early 80s with a history of severe aortic stenosis who underwent elective transcatheter aortic valve replacement using a bioprosthetic valve with balloon valvuloplasty.

Research Letter

Timolol Eyedrops in the Treatment of Acute Migraine Attacks: A Randomized Crossover Study

Abstract Full Text
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JAMA Neurol. 2018;75(8):1024-1025. doi:10.1001/jamaneurol.2018.0970

This randomized, crossover pilot study explores timolol eyedrops as an abortive migraine treatment in adults.

An Autopsy Case of Progressive Supranuclear Palsy With Incidental ATXN2 Expansion

Abstract Full Text
free access
JAMA Neurol. 2018;75(8):1025-1027. doi:10.1001/jamaneurol.2018.0652

This case report describes autopsy findings of progressive supranuclear palsy in a patient with a misdiagnosis of multiple system atrophy with predominant parkinsonism.

Comment & Response

Metachromatic Leukodystrophy: Too Frequent (Mis)Diagnosis?

Abstract Full Text
JAMA Neurol. 2018;75(8):1027. doi:10.1001/jamaneurol.2018.1515

Metachromatic Leukodystrophy: Too Frequent (Mis)Diagnosis?—Reply

Abstract Full Text
JAMA Neurol. 2018;75(8):1027-1028. doi:10.1001/jamaneurol.2018.1518
Correction

Misspelled Surname

Abstract Full Text
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JAMA Neurol. 2018;75(8):1028. doi:10.1001/jamaneurol.2018.1228

Error in Text

Abstract Full Text
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JAMA Neurol. 2018;75(8):1028. doi:10.1001/jamaneurol.2018.1407

Errors in Red and White Blood Cell Counts

Abstract Full Text
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JAMA Neurol. 2018;75(8):1028. doi:10.1001/jamaneurol.2018.1554

Error in Results Section of the Abstract

Abstract Full Text
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JAMA Neurol. 2018;75(8):1028. doi:10.1001/jamaneurol.2018.1742

Errors in the Table and Results

Abstract Full Text
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JAMA Neurol. 2018;75(8):1028. doi:10.1001/jamaneurol.2018.2068
JAMA Neurology Masthead

JAMA Neurology

Abstract Full Text
free access
JAMA Neurol. 2018;75(8):904. doi:10.1001/jamaneurol.2017.2652
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