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October 2021 - July 1959

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Issue

September 2018, Vol 75, No. 9, Pages 1035-1156

In This Issue of JAMA Neurology

Highlights

Abstract Full Text
free access
JAMA Neurol. 2018;75(9):1035. doi:10.1001/jamaneurol.2017.2656
Viewpoint

Who Should Try New Antibody Treatments for Migraine?

Abstract Full Text
JAMA Neurol. 2018;75(9):1039-1040. doi:10.1001/jamaneurol.2018.1268

This Viewpoint describes a framework for making decisions on the prescription of 4 new calcitonin gene–related peptide monoclonal antibody treatments to patients with migraine headaches.

Providing Surgery for Medically Intractable Epilepsy in Low- and Middle-Income Countries: Shifting the Focus From If to How

Abstract Full Text
JAMA Neurol. 2018;75(9):1041-1042. doi:10.1001/jamaneurol.2018.1318

This Viewpoint suggests approaches to scaling up neurosurgery in low- and middle-income countries for patients with medically intractable epilepsy.

Editorial

Risk of Dementia Outcomes Associated With Traumatic Brain Injury During Military Service

Abstract Full Text
JAMA Neurol. 2018;75(9):1043-1044. doi:10.1001/jamaneurol.2018.0347

Improving Evaluation of Patients With Cognitive Impairment With Amyloid Positron Emission Tomography

Abstract Full Text
JAMA Neurol. 2018;75(9):1045-1046. doi:10.1001/jamaneurol.2018.1010
Original Investigation

Association of Mild Traumatic Brain Injury With and Without Loss of Consciousness With Dementia in US Military Veterans

Abstract Full Text
free access
JAMA Neurol. 2018;75(9):1055-1061. doi:10.1001/jamaneurol.2018.0815

This cohort study examines the association between traumatic brain injury severity, loss of consciousness, and dementia diagnosis in US military veterans.

Association of Amyloid Positron Emission Tomography With Changes in Diagnosis and Patient Treatment in an Unselected Memory Clinic Cohort: The ABIDE Project

Abstract Full Text
free access
JAMA Neurol. 2018;75(9):1062-1070. doi:10.1001/jamaneurol.2018.1346

This cohort study explores the association between amyloid-positive and amyloid-negative results of positron emission tomography and changes in diagnosis, diagnostic confidence, and patient treatment in patients with Alzheimer disease, dementia, or cognitive decline attending a memory clinic.

Association of Retinal Ganglion Cell Layer Thickness With Future Disease Activity in Patients With Clinically Isolated Syndrome

Abstract Full Text
free access
JAMA Neurol. 2018;75(9):1071-1079. doi:10.1001/jamaneurol.2018.1011

This longitudinal cohort study investigates the association of retinal optical coherence tomographic results with future disease activity in patients with clinically isolated syndrome.

Evaluation of Galcanezumab for the Prevention of Episodic Migraine: The EVOLVE-1 Randomized Clinical Trial

Abstract Full Text
open access
JAMA Neurol. 2018;75(9):1080-1088. doi:10.1001/jamaneurol.2018.1212

This randomized clinical trial demonstrates the efficacy of 2 different dosages of galcanezumab compared with placebo in the prevention of episodic migraine in cohorts with a history of migraine.

Clinical Features of Guillain-Barré Syndrome With vs Without Zika Virus Infection, Puerto Rico, 2016

Abstract Full Text
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JAMA Neurol. 2018;75(9):1089-1097. doi:10.1001/jamaneurol.2018.1058

This analysis of public health surveillance data identifies specific clinical features and pathophysiologic mechanisms of Guillain-Barré syndrome associated with Zika virus infection among patients in Puerto Rico.

Association of Tourette Syndrome and Chronic Tic Disorders With Objective Indicators of Educational Attainment: A Population-Based Sibling Comparison Study

Abstract Full Text
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JAMA Neurol. 2018;75(9):1098-1105. doi:10.1001/jamaneurol.2018.1194

This Swedish national register-based study investigates the association of Tourette syndrome and chronic tic disorders with objectively measured educational outcomes, adjusting for psychiatric comorbidities and factors shared between siblings.

Dynamic Changes in White Matter Hyperintensities in Reversible Cerebral Vasoconstriction Syndrome

Abstract Full Text
free access
JAMA Neurol. 2018;75(9):1106-1113. doi:10.1001/jamaneurol.2018.1321

This cohort study investigates the spatiotemporal distribution and pathomechanisms of white matter hyperintensities in patients with reversible cerebral vasoconstriction syndrome.

Use of Flutemetamol F 18–Labeled Positron Emission Tomography and Other Biomarkers to Assess Risk of Clinical Progression in Patients With Amnestic Mild Cognitive Impairment

Abstract Full Text
open access
JAMA Neurol. 2018;75(9):1114-1123. doi:10.1001/jamaneurol.2018.0894

This multicenter cohort study evaluates the ability of flutemetamol F 18 and other biomarkers to assess the risk of progression from amnestic mild cognitive impairment to probable Alzheimer disease.

Interactive Associations of Vascular Risk and β-Amyloid Burden With Cognitive Decline in Clinically Normal Elderly Individuals: Findings From the Harvard Aging Brain Study

Abstract Full Text
free access
JAMA Neurol. 2018;75(9):1124-1131. doi:10.1001/jamaneurol.2018.1123

This longitudinal study assesses whether vascular risk and β-amyloid burden act additively or synergistically to promote cognitive decline in clinically normal older adults.

Review

Current Concepts in Diagnosis and Treatment of Functional Neurological Disorders

Abstract Full Text
JAMA Neurol. 2018;75(9):1132-1141. doi:10.1001/jamaneurol.2018.1264

This narrative review presents the definitions, diagnosis, and treatment of functional neurological disorders, a category of illnesses formerly known as conversion disorders.

Images in Neurology

Visual Phenomena in Occipital Lobe Epilepsy: “It’s Beautiful!”

Abstract Full Text
JAMA Neurol. 2018;75(9):1146-1147. doi:10.1001/jamaneurol.2018.2144

This case report describes an atypical onset of holocephalic headaches with transient visual phenomena that were unresponsive to migraine treatment.

JAMA Neurology Clinical Challenge

Proptosis and Double Vision in a Child

Abstract Full Text
JAMA Neurol. 2018;75(9):1142-1143. doi:10.1001/jamaneurol.2018.1271

An 8-year-old boy presented to the pediatric emergency department with 2 weeks of fatigue and 3 days of double vision, ptosis, and painless periorbital swelling of the left eye.

Neurologic Abnormalities After Atrial Fibrillation Ablative Procedure

Abstract Full Text
JAMA Neurol. 2018;75(9):1144-1145. doi:10.1001/jamaneurol.2018.1351

A man presents with acute-onset aphasia, hemiplegia, and fever after a thoracoscopic ablative procedure for atrial fibrillation. What is your diagnosis?

Comment & Response

Additional Factors Regarding Clinical Outcomes of General Anesthesia and Conscious Sedation for Acute Ischemic Stroke

Abstract Full Text
JAMA Neurol. 2018;75(9):1151. doi:10.1001/jamaneurol.2018.1844

Additional Factors Regarding Clinical Outcomes of General Anesthesia and Conscious Sedation for Acute Ischemic Stroke

Abstract Full Text
JAMA Neurol. 2018;75(9):1151-1152. doi:10.1001/jamaneurol.2018.1847

Additional Factors Regarding Clinical Outcomes of General Anesthesia and Conscious Sedation for Acute Ischemic Stroke—Reply

Abstract Full Text
JAMA Neurol. 2018;75(9):1152-1153. doi:10.1001/jamaneurol.2018.1850

Retinoids and Amyotrophic Lateral Sclerosis

Abstract Full Text
JAMA Neurol. 2018;75(9):1153. doi:10.1001/jamaneurol.2018.2242

Retinoids and Amyotrophic Lateral Sclerosis—Reply

Abstract Full Text
JAMA Neurol. 2018;75(9):1153-1154. doi:10.1001/jamaneurol.2018.2257

Orthostatic Hypotension as a Prodromal Marker of α-Synucleinopathies

Abstract Full Text
JAMA Neurol. 2018;75(9):1154. doi:10.1001/jamaneurol.2018.2248

Dietary Measures to Prevent Sudden Unexpected Death in Epilepsy

Abstract Full Text
JAMA Neurol. 2018;75(9):1155-1156. doi:10.1001/jamaneurol.2018.2245

Orthostatic Hypotension as a Prodromal Marker of α-Synucleinopathies—Reply

Abstract Full Text
JAMA Neurol. 2018;75(9):1155. doi:10.1001/jamaneurol.2018.2251

Dietary Measures to Prevent Sudden Unexpected Death in Epilepsy—Reply

Abstract Full Text
JAMA Neurol. 2018;75(9):1156. doi:10.1001/jamaneurol.2018.2254
Correction

Error in Byline

Abstract Full Text
free access
JAMA Neurol. 2018;75(9):1156. doi:10.1001/jamaneurol.2018.1257

Error in Table

Abstract Full Text
free access
JAMA Neurol. 2018;75(9):1156. doi:10.1001/jamaneurol.2018.1288

Error in Figure

Abstract Full Text
free access
JAMA Neurol. 2018;75(9):1156. doi:10.1001/jamaneurol.2018.2840
JAMA Neurology Masthead

JAMA Neurology

Abstract Full Text
free access
JAMA Neurol. 2018;75(9):1037. doi:10.1001/jamaneurol.2017.2657
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