This Viewpoint advocates for expanded usage of tenecteplase in patients with stroke as a means of avoiding coronavirus disease 2019 spread and easing potential shortages of alteplase.
This essay describes the author’s experience with transient global amnesia and the treatment he received as a patient.
This cohort study examines the association of early-life cognitive enrichment with late-life Alzheimer disease and other common dementia-related pathological changes in an autopsy sample.
This randomized clinical trial investigates whether continuous electroencephalogram is associated with reduced mortality compared with routine electroencephalogram.
This secondary analysis of a randomized clinical trial assesses the subtype of recurrent ischemic stroke after embolic stroke of underdetermined source, the interaction with treatment assignment, and the consistency of cerebral location of the qualifying and recurrent strokes in the study population of the NAVIGATE-ESUS trial.
This cross-sectional study investigates whether rapid eye movement sleep is associated with greater risk of mortality in 2 independent cohorts and explores whether another sleep stage could be driving these findings.
This cohort study examines data from original and offspring participants in the Framingham Heart Study to assess the incidence of intracerebral hemorrhage, incidence rates stratified by deep and lobar brain locations, and location-specific risk factors between 1948 and 2016.
This cohort study examines the clinical, neuroimaging, laboratory, pathologic, or treatment-related associations with outcomes after an episode of cerebral amyloid angiopathy-related inflammation.
This cohort study assesses the association between rest-activity rhythm and risk of incident Parkinson disease and explores whether this association is independent of nighttime sleep disturbances in community-dwelling older men.
This systematic review and meta-analysis examines the recurrence of ischemic stroke and possible use of patent foramen ovale closure in patients aged 60 years or older.
This genetic association study examines amyloid levels through positron emission tomographic imaging in individuals with or at risk for Alzheimer disease.
This cohort study examines brain autopsy data for the presence of quadruple misfolded proteins (tau, amyloid-β, α-synuclein, and transactive response DNA-binding protein 43) and their association with cognitive decline in older adults.
This narrative review summarizes the results of recent and ongoing randomized clinical trials of drugs for secondary stroke prevention.
This case report describes a man who applied topical metronidazole to his decubitus ulcers and experienced an uncommon neurological complication.
This case report describes a 44-year-old man who presented with positional headaches and other symptoms and was found to have spontaneous intracranial hypotension because of a cerebrospinal fluid–venous fistula.