This Viewpoint discusses how families interpret the discovery of covert consciousness in an unresponsive patient with brain injuries and how this might affect their clinical decisions, such as the withdrawal of care.
This Viewpoint discusses the need for research on the environmental factors that influence amyotrophic lateral sclerosis.
This essay describes the author’s experience interacting with an octogenarian patient with kyphosis and presbycusis and the patient’s spouse.
This randomized clinical trial examines whether outpatient integrated palliative care is associated with patient-centered outcomes and caregiver burden compared with standard care alone among patients with Parkinson disease and related disorders and their caregivers.
This nonrandomized cohort study evaluates the association between endovascular treatment and the clinical outcomes of patients with stroke and acute basilar artery occlusion, compared with patients who received standard medical treatment only.
This cohort study identifies factors associated with poor tolerability of antiseizure medications and examines temporal changes in tolerability.
This randomized clinical trial evaluates the clinical effects of zilucoplan, a subcutaneously self-administered macrocyclic peptide inhibitor of complement component 5, in a broad population of patients with moderate to severe generalized myasthenia gravis.
This study assesses the value of smartphone videos for diagnosis of epileptic seizures in adult outpatients with epilepsy.
This secondary analysis of the POINT randomized clinical trial examines the association between race and risk of early ischemic stroke recurrence after a minor ischemic stroke or transient ischemic attack among US participants.
This cross-sectional study analyzes the distributional, convergent, and predictive validity of National Institutes of Health Stroke Scale (NIHSS) values in the National Inpatient Sample.
This randomized clinical trial evaluates the efficacy and safety of 2 doses of a pharmaceutical formulation of cannabidiol vs placebo for adjunctive treatment of convulsive seizures in patients with Darvet syndrome.
This cohort study investigates whether procedural blood pressure parameters, including specific blood pressure thresholds, are associated with neurological outcomes after endovascular therapy.
This cross-sectional, longitudinal study of amyloid-β–positive individuals with mild cognitive impairment or Alzheimer disease dementia examines the factors associated with interindividual differences in brain and cognitive resilience to tau positron emission tomography load and to changes in global cognition over time.
This cohort study examines the prevalence of chronic cortical microinfarcts and the cumulative incidence and temporal dynamics of acute cortical microinfarcts in Finnish individuals with cerebral small vessel disease.
This case report describes a girl with a right frontal leptomeningeal enhancement and a boy with a left hemispheric leptomeningeal enhancement.
A 39-year-old woman presents with a 3-week history of worsening spasms in her axial and lower limb muscles, new-onset urinary retention, and sudden episodes of involuntary spasms in her abdominal muscles. What is your diagnosis?
This cross-sectional study examines paramagnetic rim sign positivity in patients with radiologically isolated syndrome.
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