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May 2020 - July 1959




May 2020, Vol 77, No. 5, Pages 537-655


Translating the Discovery of Covert Consciousness Into Clinical Practice

Abstract Full Text
JAMA Neurol. 2020;77(5):541-542. doi:10.1001/jamaneurol.2020.0232

This Viewpoint discusses how families interpret the discovery of covert consciousness in an unresponsive patient with brain injuries and how this might affect their clinical decisions, such as the withdrawal of care.

Voicing the Need for Amyotrophic Lateral Sclerosis Environmental Research

Abstract Full Text
JAMA Neurol. 2020;77(5):543-544. doi:10.1001/jamaneurol.2020.0051

This Viewpoint discusses the need for research on the environmental factors that influence amyotrophic lateral sclerosis.

On the Brain

Box of Chocolates

Abstract Full Text
JAMA Neurol. 2020;77(5):545-546. doi:10.1001/jamaneurol.2019.5040

This essay describes the author’s experience interacting with an octogenarian patient with kyphosis and presbycusis and the patient’s spouse.


JAMA Neurology—The Year in Review, 2019

Abstract Full Text
free access
JAMA Neurol. 2020;77(5):547-548. doi:10.1001/jamaneurol.2020.0240

Palliative Programs for Persons With Parkinsonism—The Next Frontier

Abstract Full Text
JAMA Neurol. 2020;77(5):548-550. doi:10.1001/jamaneurol.2019.4697
Original Investigation

Comparison of Integrated Outpatient Palliative Care With Standard Care in Patients With Parkinson Disease and Related Disorders: A Randomized Clinical Trial

Abstract Full Text
open access
JAMA Neurol. 2020;77(5):551-560. doi:10.1001/jamaneurol.2019.4992

This randomized clinical trial examines whether outpatient integrated palliative care is associated with patient-centered outcomes and caregiver burden compared with standard care alone among patients with Parkinson disease and related disorders and their caregivers.

Assessment of Endovascular Treatment for Acute Basilar Artery Occlusion via a Nationwide Prospective Registry

Abstract Full Text
JAMA Neurol. 2020;77(5):561-573. doi:10.1001/jamaneurol.2020.0156

This nonrandomized cohort study evaluates the association between endovascular treatment and the clinical outcomes of patients with stroke and acute basilar artery occlusion, compared with patients who received standard medical treatment only.

Tolerability of Antiseizure Medications in Individuals With Newly Diagnosed Epilepsy

Abstract Full Text
JAMA Neurol. 2020;77(5):574-581. doi:10.1001/jamaneurol.2020.0032

This cohort study identifies factors associated with poor tolerability of antiseizure medications and examines temporal changes in tolerability.

Clinical Effects of the Self-administered Subcutaneous Complement Inhibitor Zilucoplan in Patients With Moderate to Severe Generalized Myasthenia Gravis: Results of a Phase 2 Randomized, Double-Blind, Placebo-Controlled, Multicenter Clinical Trial

Abstract Full Text
open access has active quiz has audio
JAMA Neurol. 2020;77(5):582-592. doi:10.1001/jamaneurol.2019.5125

This randomized clinical trial evaluates the clinical effects of zilucoplan, a subcutaneously self-administered macrocyclic peptide inhibitor of complement component 5, in a broad population of patients with moderate to severe generalized myasthenia gravis.

Assessment of the Predictive Value of Outpatient Smartphone Videos for Diagnosis of Epileptic Seizures

Abstract Full Text
JAMA Neurol. 2020;77(5):593-600. doi:10.1001/jamaneurol.2019.4785

This study assesses the value of smartphone videos for diagnosis of epileptic seizures in adult outpatients with epilepsy.

Association of Black Race With Early Recurrence After Minor Ischemic Stroke or Transient Ischemic Attack: Secondary Analysis of the POINT Randomized Clinical Trial

Abstract Full Text
has active quiz
JAMA Neurol. 2020;77(5):601-605. doi:10.1001/jamaneurol.2020.0010

This secondary analysis of the POINT randomized clinical trial examines the association between race and risk of early ischemic stroke recurrence after a minor ischemic stroke or transient ischemic attack among US participants.

Distributional Validity and Prognostic Power of the National Institutes of Health Stroke Scale in US Administrative Claims Data

Abstract Full Text
JAMA Neurol. 2020;77(5):606-612. doi:10.1001/jamaneurol.2019.5061

This cross-sectional study analyzes the distributional, convergent, and predictive validity of National Institutes of Health Stroke Scale (NIHSS) values in the National Inpatient Sample.

Dose-Ranging Effect of Adjunctive Oral Cannabidiol vs Placebo on Convulsive Seizure Frequency in Dravet Syndrome: A Randomized Clinical Trial

Abstract Full Text
open access
JAMA Neurol. 2020;77(5):613-621. doi:10.1001/jamaneurol.2020.0073

This randomized clinical trial evaluates the efficacy and safety of 2 doses of a pharmaceutical formulation of cannabidiol vs placebo for adjunctive treatment of convulsive seizures in patients with Darvet syndrome.

Blood Pressure Thresholds and Neurologic Outcomes After Endovascular Therapy for Acute Ischemic Stroke: An Analysis of Individual Patient Data From 3 Randomized Clinical Trials

Abstract Full Text
JAMA Neurol. 2020;77(5):622-631. doi:10.1001/jamaneurol.2019.4838

This cohort study investigates whether procedural blood pressure parameters, including specific blood pressure thresholds, are associated with neurological outcomes after endovascular therapy.

Assessment of Demographic, Genetic, and Imaging Variables Associated With Brain Resilience and Cognitive Resilience to Pathological Tau in Patients With Alzheimer Disease

Abstract Full Text
open access
JAMA Neurol. 2020;77(5):632-642. doi:10.1001/jamaneurol.2019.5154

This cross-sectional, longitudinal study of amyloid-β–positive individuals with mild cognitive impairment or Alzheimer disease dementia examines the factors associated with interindividual differences in brain and cognitive resilience to tau positron emission tomography load and to changes in global cognition over time.

Brief Report

Temporal Dynamics of Cortical Microinfarcts in Cerebral Small Vessel Disease

Abstract Full Text
JAMA Neurol. 2020;77(5):643-647. doi:10.1001/jamaneurol.2019.5106

This cohort study examines the prevalence of chronic cortical microinfarcts and the cumulative incidence and temporal dynamics of acute cortical microinfarcts in Finnish individuals with cerebral small vessel disease.

Images in Neurology

Unilateral Leptomeningeal Enhancement in Myelin Oligodendrocyte Glycoprotein Immunoglobulin G–Associated Disease

Abstract Full Text
JAMA Neurol. 2020;77(5):648-649. doi:10.1001/jamaneurol.2020.0001

This case report describes a girl with a right frontal leptomeningeal enhancement and a boy with a left hemispheric leptomeningeal enhancement.

JAMA Neurology Clinical Challenge

Spasms and Myoclonus in a Young Woman With Hashimoto Thyroiditis

Abstract Full Text
has active quiz has multimedia
JAMA Neurol. 2020;77(5):650-651. doi:10.1001/jamaneurol.2020.0175

A 39-year-old woman presents with a 3-week history of worsening spasms in her axial and lower limb muscles, new-onset urinary retention, and sudden episodes of involuntary spasms in her abdominal muscles. What is your diagnosis?

Research Letter

Paramagnetic Rim Sign in Radiologically Isolated Syndrome

Abstract Full Text
JAMA Neurol. 2020;77(5):653-655. doi:10.1001/jamaneurol.2020.0124

This cross-sectional study examines paramagnetic rim sign positivity in patients with radiologically isolated syndrome.


Correction to Collaborator’s Name

Abstract Full Text
free access
JAMA Neurol. 2020;77(5):655. doi:10.1001/jamaneurol.2020.0749

Retracted Article in Reference Section

Abstract Full Text
free access
JAMA Neurol. 2020;77(5):655. doi:10.1001/jamaneurol.2020.0801

Error in Labels for Number at Risk

Abstract Full Text
free access
JAMA Neurol. 2020;77(5):655. doi:10.1001/jamaneurol.2020.0802
Peer Reviewers List

JAMA Neurology Peer Reviewers in 2019

Abstract Full Text
free access online only
JAMA Neurol. 2020;77(5):e200110. doi:10.1001/jamaneurol.2020.0110
JAMA Neurology Masthead

JAMA Neurology

Abstract Full Text
free access
JAMA Neurol. 2020;77(5):537. doi:10.1001/jamaneurol.2019.3199