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June 2020 - July 1959

Decade

Year

Issue

June 2020, Vol 77, No. 6, Pages 670-776

Viewpoint

Improving Access to Clinical Trials for Amyotrophic Lateral Sclerosis Treatment

Abstract Full Text
JAMA Neurol. 2020;77(6):671-672. doi:10.1001/jamaneurol.2020.0421

This Viewpoint discusses the author’s firsthand experience with clinical trials for patients with amyotrophic lateral sclerosis after her husband’s diagnosis.

Deprescribing in Epilepsy: Do No Harm

Abstract Full Text
JAMA Neurol. 2020;77(6):673-674. doi:10.1001/jamaneurol.2020.0473

This Viewpoint discusses the emerging field of deprescribing and how to advance deprescribing among patients with epilepsy.

On the Brain

Standing by the Bystander

Abstract Full Text
JAMA Neurol. 2020;77(6):678. doi:10.1001/jamaneurol.2020.0039

This essay describes the experience of a medical student encountering a mother whose son was terminally ill with Lafora body disease.

Editorial

The Spectrum of Neurologic Disease in the Severe Acute Respiratory Syndrome Coronavirus 2 Pandemic Infection: Neurologists Move to the Frontlines

Abstract Full Text
free access has active quiz
JAMA Neurol. 2020;77(6):679-680. doi:10.1001/jamaneurol.2020.1065

Triage Based on Preclinical Scores—Low-Cost Strategy for Accelerating Time to Thrombectomy

Abstract Full Text
JAMA Neurol. 2020;77(6):681-682. doi:10.1001/jamaneurol.2020.0113
Original Investigation

Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China

Abstract Full Text
free access has active quiz
JAMA Neurol. 2020;77(6):683-690. doi:10.1001/jamaneurol.2020.1127

This study investigates the neurologic manifestations of patients with coronavirus disease 2019.

Implementation of a Prehospital Stroke Triage System Using Symptom Severity and Teleconsultation in the Stockholm Stroke Triage Study

Abstract Full Text
JAMA Neurol. 2020;77(6):691-699. doi:10.1001/jamaneurol.2020.0319

This cohort study examines a system for prehospital triage for Swedish patients with suspected acute stroke.

Association of Stress-Related Disorders With Subsequent Neurodegenerative Diseases

Abstract Full Text
has active quiz
JAMA Neurol. 2020;77(6):700-709. doi:10.1001/jamaneurol.2020.0117

This cohort study analyzes Swedish patient registries to identify the familial, lifestyle, cardiovascular, and other risk factors in the later development of neurodegenerative diseases among adults with stress-related disorders compared with their siblings and people without the condition.

Association of Late-Onset Unprovoked Seizures of Unknown Etiology With the Risk of Developing Dementia in Older Veterans

Abstract Full Text
has active quiz
JAMA Neurol. 2020;77(6):710-715. doi:10.1001/jamaneurol.2020.0187

This cohort study evaluates whether incident late-onset unprovoked seizures of unknown etiology are associated with a higher risk of developing dementia among older US veterans.

Association of Sleep-Disordered Breathing With Alzheimer Disease Biomarkers in Community-Dwelling Older Adults: A Secondary Analysis of a Randomized Clinical Trial

Abstract Full Text
JAMA Neurol. 2020;77(6):716-724. doi:10.1001/jamaneurol.2020.0311

This cross-sectional study seeks to determine which brain changes, including changes in amyloid deposition, gray matter volume, perfusion, and glucose metabolism, are associated with the presence of sleep-disordered breathing in older individuals who are cognitively unimpaired.

Effect of In-Hospital Remote Ischemic Perconditioning on Brain Infarction Growth and Clinical Outcomes in Patients With Acute Ischemic Stroke: The RESCUE BRAIN Randomized Clinical Trial

Abstract Full Text
JAMA Neurol. 2020;77(6):725-734. doi:10.1001/jamaneurol.2020.0326

This randomized clinical trial examines whether in-hospital treatment with remote ischemic perconditioning that is administered within 6 hours of symptom onset, with or without reperfusion therapy, can reduce brain infarction volume growth in patients with acute ischemic stroke.

Association of Factors With Elevated Amyloid Burden in Clinically Normal Older Individuals

Abstract Full Text
has audio
JAMA Neurol. 2020;77(6):735-745. doi:10.1001/jamaneurol.2020.0387

This cross-sectional analysis examines the association of elevated amyloid with demographic and lifestyle factors, apolipoprotein E, neuropsychological testing, and self- and study partner reports of cognitive function among participants in the A4 Study.

Identification of Risk Loci for Parkinson Disease in Asians and Comparison of Risk Between Asians and Europeans: A Genome-Wide Association Study

Abstract Full Text
JAMA Neurol. 2020;77(6):746-754. doi:10.1001/jamaneurol.2020.0428

This genetic association study compares gene loci for Parkinson Disease in cohorts of Asian and European individuals with Parkinson disease.

Special Communication

Seven-Year Experience From the National Institute of Neurological Disorders and Stroke–Supported Network for Excellence in Neuroscience Clinical Trials

Abstract Full Text
JAMA Neurol. 2020;77(6):755-763. doi:10.1001/jamaneurol.2020.0367

This Special Communication discusses the formation of the National Institute of Neurological Disorders and Stroke Network for Excellence in Neuroscience Clinical Trials (NeuroNEXT) and what NeuroNEXT has accomplished within the first 7 years.

Clinical Implications of Basic Neuroscience Research

Huntingtin-Lowering Therapies for Huntington Disease: A Review of the Evidence of Potential Benefits and Risks

Abstract Full Text
JAMA Neurol. 2020;77(6):764-772. doi:10.1001/jamaneurol.2020.0299

This review examines data from human and animal studies of the altered huntingtin protein associated with Huntington disease to assess the risk-benefit profile of huntingtin-lowering therapies for the treatment of people with Huntington disease.

Comment & Response

Uncertain Association Between Concussion and Hypogonadism

Abstract Full Text
JAMA Neurol. 2020;77(6):774. doi:10.1001/jamaneurol.2020.0470

Uncertain Association Between Concussion and Hypogonadism—Reply

Abstract Full Text
JAMA Neurol. 2020;77(6):774-775. doi:10.1001/jamaneurol.2020.0476

Magnetic Resonance Imaging for Acute Minor Neurological Symptoms: Good for Ruling Stroke in, Not Out

Abstract Full Text
JAMA Neurol. 2020;77(6):775-776. doi:10.1001/jamaneurol.2020.0661
Correction

Error to Reference List

Abstract Full Text
free access
JAMA Neurol. 2020;77(6):776. doi:10.1001/jamaneurol.2020.1507
JAMA Neurology Masthead

JAMA Neurology

Abstract Full Text
free access
JAMA Neurol. 2020;77(6):670. doi:10.1001/jamaneurol.2019.3204
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