This Viewpoint discusses white matter degeneration as a potentially treatable target for reducing cognitive impairment and dementia.
This article compares the author’s experience with mechanics who refused to believe that a car had a unique malfunction with her experience with clinicians who could not diagnose her rare disease.
This cohort study investigates the association of long-term exposure to air pollution with dementia and evaluates the role of cardiovascular disease in the association among participants of the population-based Swedish National Study on Aging and Care in Kungsholmen.
This cohort study assesses whether blood pressure levels are associated with racial differences in cognitive decline.
This cohort study assesses whether the risk of macrovascular events and mortality differs among people with multiple sclerosis compared with a matched population without multiple sclerosis in England.
This diagnostic study explores whether positron emission tomography with [18F]flortaucipir can detect tau pathology and Alzheimer disease neuropathologic changes in terminally ill adults with or without dementia.
This cluster randomized clinical trial sought to examine whether adding enhanced paramedic assessment to standard care would result in increased rates of thrombolysis in patients experiencing stroke.
This study combined data from 35 independent case-control, family-based, and longitudinal cohorts that examined Alzheimer disease to determine if Klotho-VS heterozygosity is associated with reduced Alzheimer disease risk and β-amyloid (Aβ) pathology in individuals who carry APOE4.
This cohort study describes trends among rural and urban patients with acute ischemic stroke or transient ischemic attack in the type of health care centers to which patients were admitted, what care was provided, and patient outcomes.
This study confirms the existence of dermatomyositis sine dermatitis, determines its prevalence, and characterizes the serologic features of dermatomyositis sine dermatitis.
This Special Communication describes new information on strokes associated with patent foramen ovale from randomized clinical trials and meta-analyses and proposes a new clinical approach to the categorization of such strokes.
This systematic review uses articles published between 1985 and 2016 to examine family history rates and inheritance patterns of cluster headache.
This case report describes a 47-year-old man with Meniere disease with recurrent vertigo that caused Tumarkin drop attacks.
This case report describes a man with paraneoplastic neurological syndrome with paraneoplastic encephalomyelitis and small cell lung cancer who also had unusual pathophysiological features visible on magnetic resonance imaging.
This comparative effectiveness research study examines propensity scores adjustment in multiple sclerosis studies comparing disease-modifying treatments.
This article provides in vivo images of the intracranial vasa vasorum taken by optical coherence tomography.
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